Mitigation of liquid-liquid phase separation of a monoclonal antibody by mutations of negative charges on the Fab surface.

by Tatsuji Matsuoka, Ryuki Miyauchi, Nobumi Nagaoka, Jun Hasegawa
Published 2020-01-01

Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification.

by Mitsuhiro Iwamoto, Yukiko Sekiguchi, Kensuke Nakamura, Yoshirou Kawaguchi, Takeshi Honda, Jun Hasegawa
Published 2018-01-01

Extraction of high-intensity ion beams from a laser plasma by a pulsed spherical diode

by Yoshiyuki Oguri, Ken-ichi Kashiwagi, Jun-ichi Kaneko, Jun Hasegawa, Masahiro Yoshida, Masao Ogawa
Published 2005-06-01

Change in and long-term investigation of neuro-otologic disorders in disaster-stricken Fukushima prefecture: retrospective cohort study before and after the Great East Japan Earthq...

by Jun Hasegawa, Hiroshi Hidaka, Shinichi Kuriyama, Taku Obara, Ken Hashimoto, Yutaka Tateda, Yuri Okumura, Toshimitsu Kobayashi, Yukio Katori
Published 2015-01-01

MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancer.

by Satoko Nishimura, Makiko Uno, Yasuyuki Kaneta, Keisuke Fukuchi, Haruyuki Nishigohri, Jun Hasegawa, Hironobu Komori, Shigeki Takeda, Katsuhiko Enomoto, Futoshi Nara, Toshinori Agatsuma
Published 2012-01-01

Breast Signet-ring Cell Lobular Carcinoma Presenting with Duodenal Obstruction and Acute Pancreatitis

by Tomoi Sato, Ichiro Muto, Masaki Hasegawa, Takashi Aono, Takayuki Okada, Jun Hasegawa, Shigeto Makino, Hitoshi Kameyama, Ryo Tanaka, Masao Sekiya, Katsuyoshi Hatakeyama
Published 2007-07-01

Gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor: a case of a rare malignancy

by Kazuki Moro, Masayuki Nagahashi, Tetsuya Naito, Yu Nagai, Tomohiro Katada, Masahiro Minagawa, Jun Hasegawa, Tatsuo Tani, Naohiro Shimakage, Hiroyuki Usuda, Emmanuel Gabriel, Tsutomu Kawaguchi, Kazuaki Takabe, Toshifumi Wakai
Published 2017-05-01

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the afucosylated, humanized anti-EPHA2 antibody DS-8895a: a first-in-human phase I dose escalation and dose expansio...

by Kohei Shitara, Taroh Satoh, Satoru Iwasa, Kensei Yamaguchi, Kei Muro, Yoshito Komatsu, Tomohiro Nishina, Taito Esaki, Jun Hasegawa, Yasuyuki Kakurai, Emi Kamiyama, Tomoko Nakata, Kota Nakamura, Hayato Sakaki, Ichinosuke Hyodo
Published 2019-08-01