Regulation of immune checkpoint blockade efficacy in breast cancer by FIP200: A canonical-autophagy-independent function

by Syn Kok Yeo, Jun-Lin Guan
Published 2020-07-01

FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

by Ritama Paul, Ming Luo, Xueying Mo, Jason Lu, Syn Kok Yeo, Jun-Lin Guan
Published 2020-06-01

Correction to: FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

by Ritama Paul, Ming Luo, Xueying Mo, Jason Lu, Syn Kok Yeo, Jun-Lin Guan
Published 2020-06-01

Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos.

by Nicoletta I Petridou, Panayiota Stylianou, Neophytos Christodoulou, Daniel Rhoads, Jun-Lin Guan, Paris A Skourides
Published 2012-01-01

Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis.

by Xi Chen, Min Li, Daohong Chen, Wentao Gao, Jun-Lin Guan, Massaki Komatsu, Xiao-Ming Yin
Published 2012-01-01

Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer

by Syn Kok Yeo, Xiaoting Zhu, Takako Okamoto, Mingang Hao, Cailian Wang, Peixin Lu, Long Jason Lu, Jun-Lin Guan
Published 2020-08-01

PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654Summary

by Chenxi Gao, Guangming Chen, Dennis Han Zhang, Judy Zhang, Shih-Fan Kuan, Wenhuo Hu, Farzad Esni, Xuan Gao, Jun-Lin Guan, Edward Chu, Jing Hu
Published 2019-01-01

Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer

by Yongguang Yang, Marissa Leonard, Zhenhua Luo, Syn Yeo, Gregory Bick, Mingang Hao, Chunmiao Cai, Mahmoud Charif, Jiang Wang, Jun-Lin Guan, Elyse E. Lower, Xiaoting Zhang
Published 2021-03-01

FIP200 restricts RNA virus infection by facilitating RIG-I activation

by Lingyan Wang, Kun Song, Wenzhuo Hao, Yakun Wu, Girish Patil, Fang Hua, Yiwen Sun, Chaoqun Huang, Jerry Ritchey, Clinton Jones, Lin Liu, Jun-Lin Guan, Shitao Li
Published 2021-07-01

Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1

by Edward Kim, Yuan Wang, Sun-Jung Kim, Miriam Bornhorst, Emmanuelle S Jecrois, Todd E Anthony, Chenran Wang, Yi E Li, Jun-Lin Guan, Geoffrey G Murphy, Yuan Zhu
Published 2014-12-01

Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells

by Hongbao Fang, Shanshan Geng, Mingang Hao, Qixin Chen, Minglun Liu, Chunyan Liu, Zhiqi Tian, Chengjun Wang, Takanori Takebe, Jun-Lin Guan, Yuncong Chen, Zijian Guo, Weijiang He, Jiajie Diao
Published 2021-01-01

Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis

by Houjun Xia, Shasha Li, Xiong Li, Weichao Wang, Yingjie Bian, Shuang Wei, Sara Grove, Weimin Wang, Linda Vatan, J. Rebecca Liu, Karen McLean, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Ilona Kryczek, Weiping Zou
Published 2020-09-01

Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage

by Shan Deng, Kobina Essandoh, Xiaohong Wang, Yutian Li, Wei Huang, Jing Chen, Jiangtong Peng, Ding-Sheng Jiang, Xingjiang Mu, Chenran Wang, Tianqing Peng, Jun-Lin Guan, Yigang Wang, Anil Jegga, Kai Huang, Guo-Chang Fan
Published 2020-05-01

Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.

by Dongyan Wang, Mitchell A Olman, Jerry Stewart, Russell Tipps, Ping Huang, Paul W Sanders, Eric Toline, Richard A Prayson, Jeongwu Lee, Robert J Weil, Cheryl A Palmer, G Yancey Gillespie, Wei Michael Liu, Russell O Pieper, Jun-Lin Guan, Candece L Gladson
Published 2011-01-01

Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase

by Praveena S. Thiagarajan, Maksim Sinyuk, Soumya M. Turaga, Erin E. Mulkearns-Hubert, James S. Hale, Vinay Rao, Abeba Demelash, Caner Saygin, Arnab China, Tyler J. Alban, Masahiro Hitomi, Luke A. Torre-Healy, Alvaro G. Alvarado, Awad Jarrar, Andrew Wiechert, Valery Adorno-Cruz, Paul L. Fox, Benjamin C. Calhoun, Jun-Lin Guan, Huiping Liu, Ofer Reizes, Justin D. Lathia
Published 2018-02-01