A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.

by Osamu Hashizume, Haruka Yamanashi, Makoto M Taketo, Kazuto Nakada, Jun-Ichi Hayashi
Published 2015-01-01

New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice.

by Liqin Cao, Hiroshi Shitara, Michihiko Sugimoto, Jun-Ichi Hayashi, Kuniya Abe, Hiromichi Yonekawa
Published 2009-12-01

Preparation of Nitrogen-Doped Porous Carbon and its Water Adsorption Behaviour

by Toshihide Horikawa, Noriyuki Sakao, Jun'ichi Hayashi, D. D. Do, Masahiro Katoh, Ken-Ichiro Sotowa
Published 2013-03-01

Mitochondrial DNA mutations regulate metastasis of human breast cancer cells.

by Hirotake Imanishi, Keisuke Hattori, Reiko Wada, Kaori Ishikawa, Sayaka Fukuda, Keizo Takenaga, Kazuto Nakada, Jun-ichi Hayashi
Published 2011-01-01

Mitochondrial DNA mutations in mutator mice confer respiration defects and B-cell lymphoma development.

by Takayuki Mito, Yoshiaki Kikkawa, Akinori Shimizu, Osamu Hashizume, Shun Katada, Hirotake Imanishi, Azusa Ota, Yukina Kato, Kazuto Nakada, Jun-Ichi Hayashi
Published 2013-01-01

A 5-bp insertion in Mip causes recessive congenital cataract in KFRS4/Kyo rats.

by Kei Watanabe, Kenta Wada, Tomoko Ohashi, Saki Okubo, Kensuke Takekuma, Ryoichi Hashizume, Jun-Ichi Hayashi, Tadao Serikawa, Takashi Kuramoto, Yoshiaki Kikkawa
Published 2012-01-01

A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome

by Yoshihito Kishita, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi, Takuya Fushimi, Masaru Shimura, Masakazu Kohda, Akira Ohtake, Kei Murayama, Yasushi Okazaki
Published 2021-05-01

Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system.

by Hirotake Imanishi, Gaku Takibuchi, Toshihiko Kobayashi, Kaori Ishikawa, Kazuto Nakada, Masayuki Mori, Yoshiaki Kikkawa, Keizo Takenaga, Noriko Toyama-Sorimachi, Jun-Ichi Hayashi
Published 2013-01-01

Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner.

by Chisato Sumi, Akihisa Okamoto, Hiromasa Tanaka, Kenichiro Nishi, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Takehiko Adachi, Jun-Ichi Hayashi, Keizo Takenaga, Kiichi Hirota
Published 2018-01-01