Motor Improvement-Related Regional Cerebral Blood Flow Changes in Parkinson’s Disease in Response to Antiparkinsonian Drugs

by Soutarou Taguchi, Nachi Tanabe, Jun-ichi Niwa, Manabu Doyu
Published 2019-01-01

Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies

by Yohei Iguchi, Masahisa Katsuno, Shinnosuke Takagi, Shinsuke Ishigaki, Jun-ichi Niwa, Masato Hasegawa, Fumiaki Tanaka, Gen Sobue
Published 2012-03-01

Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity

by Shinsuke Ishigaki, Jun-ichi Niwa, Shin-ichi Yamada, Miho Takahashi, Takashi Ito, Jun Sone, Manabu Doyu, Fumihiko Urano, Gen Sobue
Published 2007-02-01

RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-43.

by Shinnosuke Takagi, Yohei Iguchi, Masahisa Katsuno, Shinsuke Ishigaki, Kensuke Ikenaka, Yusuke Fujioka, Daiyu Honda, Jun-ichi Niwa, Fumiaki Tanaka, Hirohisa Watanabe, Hiroaki Adachi, Gen Sobue
Published 2013-01-01

Antiparkinsonian drugs as potent contributors to nocturnal sleep in patients with Parkinson's disease.

by Soutarou Taguchi, Hirofumi Koide, Hiroko Oiwa, Miku Hayashi, Kazuhiro Ogawa, Chihiro Ito, Koji Nakashima, Tomoko Yuasa, Akihiro Yasumoto, Hiroaki Ando, Akifumi Fujikake, Takaaki Fukuoka, Keisuke Tokui, Masayuki Izumi, Yuka Tsunoda, Yuichi Kawagashira, Yohei Okada, Jun-Ichi Niwa, Manabu Doyu
Published 2021-01-01