Current smoking status may be associated with overt albuminuria in female patients with type 1 diabetes mellitus: a cross-sectional study

by Kenta Okada, Jun-ichi Osuga, Kazuhiko Kotani, Hiroaki Yagyu, Michiaki Miyamoto, Shoichiro Nagasaka, Shun Ishibashi
Published 2012-08-01

Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity

by Manabu Takahashi, Hiroaki Yagyu, Fumiko Tazoe, Shuichi Nagashima, Taichi Ohshiro, Kenta Okada, Jun-ichi Osuga, Ira J. Goldberg, Shun Ishibashi
Published 2013-04-01

Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages[S]

by Kent Sakai, Masaki Igarashi, Daisuke Yamamuro, Taichi Ohshiro, Shuichi Nagashima, Manabu Takahashi, Bolormaa Enkhtuvshin, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Shun Ishibashi
Published 2014-10-01

Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver

by Shuichi Nagashima, Hiroaki Yagyu, Ryuichi Tozawa, Fumiko Tazoe, Manabu Takahashi, Tetsuya Kitamine, Daisuke Yamamuro, Kent Sakai, Motohiro Sekiya, Hiroaki Okazaki, Jun-ichi Osuga, Akira Honda, Shun Ishibashi
Published 2015-05-01

Esterification of 4β-hydroxycholesterol and other oxysterols in human plasma occurs independently of LCAT

by Daisuke Yamamuro, Hisataka Yamazaki, Jun-ichi Osuga, Kenta Okada, Tetsuji Wakabayashi, Akihito Takei, Shoko Takei, Manabu Takahashi, Shuichi Nagashima, Adriaan G. Holleboom, Masayuki Kuroda, Hideaki Bujo, Shun Ishibashi
Published 2020-09-01

Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence[S]

by Masaki Igarashi, Jun-ichi Osuga, Masashi Isshiki, Motohiro Sekiya, Hiroaki Okazaki, Satoru Takase, Mikio Takanashi, Keisuke Ohta, Masayoshi Kumagai, Makiko Nishi, Toshiro Fujita, Ryozo Nagai, Takashi Kadowaki, Shun Ishibashi
Published 2010-02-01

Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages[S]

by Motohiro Sekiya, Daisuke Yamamuro, Taichi Ohshiro, Akira Honda, Manabu Takahashi, Masayoshi Kumagai, Kent Sakai, Shuichi Nagashima, Hiroshi Tomoda, Masaki Igarashi, Hiroaki Okazaki, Hiroaki Yagyu, Jun-ichi Osuga, Shun Ishibashi
Published 2014-10-01

Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia

by Ken Ohashi, Shun Ishibashi, Jun-ichi Osuga, Ryu-ichi Tozawa, Kenji Harada, Naoya Yahagi, Futoshi Shionoiri, Yoko Iizuka, Yoshiaki Tamura, Ryozo Nagai, D. Roger Illingworth, Takanari Gotoda, Nobuhiro Yamada
Published 2000-08-01

Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice

by Hiroaki Yagyu, Shun Ishibashi, Zhong Chen, Jun-ichi Osuga, Mitsuyo Okazaki, Stéphane Perrey, Tetsuya Kitamine, Masako Shimada, Ken Ohashi, Kenji Harada, Futoshi Shionoiri, Naoya Yahagi, Takanari Gotoda, Yoshio Yazaki, Nobuhiro Yamada
Published 1999-09-01

Dual regulation of mouse Δ5- and Δ6-desaturase gene expression by SREBP-1 and PPARα

by Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, Michiyo Amemiya-Kudo, Tomohiro Yoshikawa, Alyssa H. Hasty, Yoshiaki Tamura, Jun-ichi Osuga, Hiroaki Okazaki, Yoko Iizuka, Akimitsu Takahashi, Hirohito Sone, Takanari Gotoda, Shun Ishibashi, Nobuhiro Yamada
Published 2002-01-01

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs

by Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, Tomohiro Yoshikawa, Michiyo Amemiya-Kudo, Alyssa H. Hasty, Hiroaki Okazaki, Yoshiaki Tamura, Yoko Iizuka, Ken Ohashi, Jun-ichi Osuga, Akimitsu Takahashi, Shigeru Yato, Hirohito Sone, Shun Ishibashi, Nobuhiro Yamada
Published 2002-06-01

SREBP-1-independent regulation of lipogenic gene expression in adipocytes

by Motohiro Sekiya, Naoya Yahagi, Takashi Matsuzaka, Yoshinori Takeuchi, Yoshimi Nakagawa, Haruka Takahashi, Hiroaki Okazaki, Yoko Iizuka, Ken Ohashi, Takanari Gotoda, Shun Ishibashi, Ryozo Nagai, Tsutomu Yamazaki, Takashi Kadowaki, Nobuhiro Yamada, Jun-ichi Osuga, Hitoshi Shimano
Published 2007-07-01

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

by Michiyo Amemiya-Kudo, Hitoshi Shimano, Alyssa H. Hasty, Naoya Yahagi, Tomohiro Yoshikawa, Takashi Matsuzaka, Hiroaki Okazaki, Yoshiaki Tamura, Yoko Iizuka, Ken Ohashi, Jun-ichi Osuga, Kenji Harada, Takanari Gotoda, Ryuichiro Sato, Satoshi Kimura, Shun Ishibashi, Nobuhiro Yamada
Published 2002-08-01

Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis

by Motohiro Sekiya, Jun-ichi Osuga, Naoya Yahagi, Hiroaki Okazaki, Yoshiaki Tamura, Masaki Igarashi, Satoru Takase, Kenji Harada, Sachiko Okazaki, Yoko Iizuka, Ken Ohashi, Hiroaki Yagyu, Mitsuyo Okazaki, Takanari Gotoda, Ryozo Nagai, Takashi Kadowaki, Hitoshi Shimano, Nobuhiro Yamada, Shun Ishibashi
Published 2008-08-01

Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver

by Hiroaki Okazaki, Fumiko Tazoe, Sachiko Okazaki, Naoyuki Isoo, Kazuhisa Tsukamoto, Motohiro Sekiya, Naoya Yahagi, Yoko Iizuka, Ken Ohashi, Tetsuya Kitamine, Ryu-ichi Tozawa, Toshihiro Inaba, Hiroaki Yagyu, Mitsuyo Okazaki, Hitoshi Shimano, Norihito Shibata, Hiroyuki Arai, Ryo-zo Nagai, Takashi Kadowaki, Jun-ichi Osuga, Shun Ishibashi
Published 2006-09-01