Triple combination antiviral drug (TCAD) composed of amantadine, oseltamivir, and ribavirin impedes the selection of drug-resistant influenza A virus.

by Justin D Hoopes, Elizabeth M Driebe, Erin Kelley, David M Engelthaler, Paul S Keim, Alan S Perelson, Libin Rong, Gregory T Went, Jack T Nguyen
Published 2011-01-01

Triple combination of amantadine, ribavirin, and oseltamivir is highly active and synergistic against drug resistant influenza virus strains in vitro.

by Jack T Nguyen, Justin D Hoopes, Minh H Le, Donald F Smee, Amy K Patick, Dennis J Faix, Patrick J Blair, Menno D de Jong, Mark N Prichard, Gregory T Went
Published 2010-01-01