Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

by George D. Mcilroy, Sharon E. Mitchell, Weiping Han, Mirela Delibegović, Justin J. Rochford
Published 2020-01-01

The burden of metabolic syndrome on osteoarthritic joints

by Bruce M. Dickson, Anke J. Roelofs, Justin J. Rochford, Heather M. Wilson, Cosimo De Bari
Published 2019-12-01

Promethin Is a Conserved Seipin Partner Protein

by Inês G. Castro, Michal Eisenberg-Bord, Elisa Persiani, Justin J. Rochford, Maya Schuldiner, Maria Bohnert
Published 2019-03-01

Neuroanatomical characterisation of the expression of the lipodystrophy and motor-neuropathy gene Bscl2 in adult mouse brain.

by Alastair S Garfield, Wai S Chan, Rowena J Dennis, Daisuke Ito, Lora K Heisler, Justin J Rochford
Published 2012-01-01

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

by Md. Mesbah Uddin Talukder, M.F. Michelle Sim, Stephen O'Rahilly, J. Michael Edwardson, Justin J. Rochford
Published 2015-03-01

<i>Bscl2</i> Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy

by Ahlima Roumane, George D. Mcilroy, Arda Balci, Weiping Han, Mirela Delibegović, Massimiliano Baldassarre, Philip Newsholme, Justin J. Rochford
Published 2021-01-01

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

by M. F. Michelle Sim, Elisa Persiani, Md. Mesbah Uddin Talukder, George D. Mcilroy, Ahlima Roumane, J. Michael Edwardson, Justin J. Rochford
Published 2020-02-01

Phosphoprotein enriched in astrocytes (PEA)-15 is a novel regulator of adipose tissue expansion

by Pola J. Verschoor, Fiona H. Greig, Justin J. Rochford, Giovanni Levate, Mirela Delibegovic, Dawn Thompson, Alasdair Leeson-Payne, Ruta Dekeryte, Ruth Banks, Joe W. Ramos, Graeme F. Nixon
Published 2021-03-01

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

by George D. Mcilroy, Karla Suchacki, Anke J. Roelofs, Wulin Yang, Yanyun Fu, Bo Bai, Robert J. Wallace, Cosimo De Bari, William P. Cawthorn, Weiping Han, Mirela Delibegović, Justin J. Rochford
Published 2018-04-01

Lorcaserin improves glycemic control via a melanocortin neurocircuit

by Luke K. Burke, Emmanuel Ogunnowo-Bada, Teodora Georgescu, Claudia Cristiano, Pablo B. Martinez de Morentin, Lourdes Valencia Torres, Giuseppe D'Agostino, Christine Riches, Nicholas Heeley, Yue Ruan, Marcelo Rubinstein, Malcolm J. Low, Martin G. Myers, Justin J. Rochford, Mark L. Evans, Lora K. Heisler
Published 2017-10-01

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

by Luke K. Burke, Barbora Doslikova, Giuseppe D'Agostino, Megan Greenwald-Yarnell, Teodora Georgescu, Raffaella Chianese, Pablo B. Martinez de Morentin, Emmanuel Ogunnowo-Bada, Celine Cansell, Lourdes Valencia-Torres, Alastair S. Garfield, John Apergis-Schoute, Daniel D. Lam, John R. Speakman, Marcelo Rubinstein, Malcolm J. Low, Justin J. Rochford, Martin G. Myers, Mark L. Evans, Lora K. Heisler
Published 2016-03-01

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

by Yang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, M. Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jesse M. Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G. Doench, J. Michael Edwardson, Justin J. Rochford, Evan D. Rosen, Amit R. Majithia
Published 2019-06-01