Role of Leptin in Cardiovascular Diseases

by Mareike S. Poetsch, Anna Strano, Kaomei Guan
Published 2020-06-01

Repurposing Antidiabetic Drugs for Cardiovascular Disease

by Mario Schubert, Sinah Hansen, Julian Leefmann, Kaomei Guan
Published 2020-09-01

Blebbistatin protects iPSC-CMs from hypercontraction and facilitates automated patch-clamp based electrophysiological study

by Wener Li, Xiaojing Luo, Ying Ulbricht, Kaomei Guan
Published 2021-10-01

IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency

by Xiaojing Luo, Wener Li, Karolina Künzel, Sarah Henze, Lukas Cyganek, Lukas Cyganek, Anna Strano, Mareike S. Poetsch, Mario Schubert, Kaomei Guan, Kaomei Guan
Published 2020-08-01

Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation

by Wener Li, Michael Stauske, Michael Stauske, Xiaojing Luo, Stefan Wagner, Stefan Wagner, Meike Vollrath, Carola S. Mehnert, Mario Schubert, Lukas Cyganek, Lukas Cyganek, Simin Chen, Sayed-Mohammad Hasheminasab, Sayed-Mohammad Hasheminasab, Gerald Wulf, Ali El-Armouche, Lars S. Maier, Lars S. Maier, Gerd Hasenfuss, Gerd Hasenfuss, Kaomei Guan, Kaomei Guan, Kaomei Guan
Published 2020-10-01

Establishment of an automated patch-clamp platform for electrophysiological and pharmacological evaluation of hiPSC-CMs

by Wener Li, Xiaojing Luo, Ying Ulbricht, Michael Wagner, Christopher Piorkowski, Ali El-Armouche, Kaomei Guan
Published 2019-12-01

Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D

by Carina Gröschel, Carina Gröschel, Daniela Hübscher, Daniela Hübscher, Jessica Nolte, Sebastian Monecke, Sebastian Monecke, André Sasse, Leslie Elsner, Walter Paulus, Claudia Trenkwalder, Bojan Polić, Ahmed Mansouri, Ahmed Mansouri, Kaomei Guan, Kaomei Guan, Ralf Dressel, Ralf Dressel
Published 2017-07-01

Generation of iPSC lines from CPVT patient carrying heterozygous mutation p.A2254V in the ryanodine receptor 2 gene

by Wener Li, Sarah Henze, Xiaojing Luo, Ying Ulbricht, Anja Richter, Nataliya Di Donato, Arthur A.M. Wilde, Kaomei Guan
Published 2021-05-01

Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.

by Vanessa Kruse, Carina Hamann, Sebastian Monecke, Lukas Cyganek, Leslie Elsner, Daniela Hübscher, Lutz Walter, Katrin Streckfuss-Bömeke, Kaomei Guan, Ralf Dressel
Published 2015-01-01

A calcineurin-mediated scaling mechanism that controls a K+-leak channel to regulate morphogen and growth factor transcription

by Chao Yi, Tim WGM Spitters, Ezz Al-Din Ahmed Al-Far, Sen Wang, TianLong Xiong, Simian Cai, Xin Yan, Kaomei Guan, Michael Wagner, Ali El-Armouche, Christopher L Antos
Published 2021-04-01

Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure

by Andrea Ruiz-Velasco, Min Zi, Susanne S Hille, Tayyiba Azam, Namrita Kaur, Juwei Jiang, Binh Nguyen, Karolina Sekeres, Pablo Binder, Lucy Collins, Fay Pu, Han Xiao, Kaomei Guan, Norbert Frey, Elizabeth J Cartwright, Oliver J Müller, Xin Wang, Wei Liu
Published 2020-03-01

Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (IK,ACh)

by Christiaan C. Veerman, Isabella Mengarelli, Charlotte D. Koopman, Ronald Wilders, Shirley C. van Amersfoorth, Diane Bakker, Rianne Wolswinkel, Mariam Hababa, Teun P. de Boer, Kaomei Guan, James Milnes, Elisabeth M. Lodder, Jeroen Bakkers, Arie O. Verkerk, Connie R. Bezzina
Published 2019-07-01

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

by Arpita Chowdhury, Abhishek Aich, Gaurav Jain, Katharina Wozny, Christian Lüchtenborg, Magnus Hartmann, Olaf Bernhard, Martina Balleiniger, Ezzaldin Ahmed Alfar, Anke Zieseniss, Karl Toischer, Kaomei Guan, Silvio O. Rizzoli, Britta Brügger, Andrè Fischer, Dörthe M. Katschinski, Peter Rehling, Jan Dudek
Published 2018-10-01

Naturally Prefabricated Marine Biomaterials: Isolation and Applications of Flat Chitinous 3D Scaffolds from <i>Ianthella labyrinthus</i> (Demospongiae: Verongiida)

by Mario Schubert, Björn Binnewerg, Alona Voronkina, Lyubov Muzychka, Marcin Wysokowski, Iaroslav Petrenko, Valentine Kovalchuk, Mikhail Tsurkan, Rajko Martinovic, Nicole Bechmann, Viatcheslav N. Ivanenko, Andriy Fursov, Oleg B. Smolii, Jane Fromont, Yvonne Joseph, Stefan R. Bornstein, Marco Giovine, Dirk Erpenbeck, Kaomei Guan, Hermann Ehrlich
Published 2019-10-01

Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Do not Improve with Carnitine Supplementation

by Arie O. Verkerk, Arie O. Verkerk, Suzan J. G. Knottnerus, Suzan J. G. Knottnerus, Vincent Portero, Jeannette C. Bleeker, Jeannette C. Bleeker, Sacha Ferdinandusse, Kaomei Guan, Lodewijk IJlst, Gepke Visser, Gepke Visser, Ronald J. A. Wanders, Frits A. Wijburg, Connie R. Bezzina, Isabella Mengarelli, Riekelt H. Houtkooper
Published 2021-01-01

Naturally Drug-Loaded Chitin: Isolation and Applications

by Valentine Kovalchuk, Alona Voronkina, Björn Binnewerg, Mario Schubert, Liubov Muzychka, Marcin Wysokowski, Mikhail V. Tsurkan, Nicole Bechmann, Iaroslav Petrenko, Andriy Fursov, Rajko Martinovic, Viatcheslav N. Ivanenko, Jane Fromont, Oleg B. Smolii, Yvonne Joseph, Marco Giovine, Dirk Erpenbeck, Michael Gelinsky, Armin Springer, Kaomei Guan, Stefan R. Bornstein, Hermann Ehrlich
Published 2019-10-01

Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates

by Suzan J. G. Knottnerus, Isabella Mengarelli, Rob C. I. Wüst, Antonius Baartscheer, Jeannette C. Bleeker, Ruben Coronel, Sacha Ferdinandusse, Kaomei Guan, Lodewijk IJlst, Wener Li, Xiaojing Luo, Vincent M. Portero, Ying Ulbricht, Gepke Visser, Ronald J. A. Wanders, Frits A. Wijburg, Arie O. Verkerk, Riekelt H. Houtkooper, Connie R. Bezzina
Published 2020-04-01

Spider Chitin: An Ultrafast Microwave-Assisted Method for Chitin Isolation from <i>Caribena versicolor</i> Spider Molt Cuticle

by Tomasz Machałowski, Marcin Wysokowski, Mikhail V. Tsurkan, Roberta Galli, Christian Schimpf, David Rafaja, Erica Brendler, Christine Viehweger, Sonia Żółtowska-Aksamitowska, Iaroslav Petrenko, Katarzyna Czaczyk, Michael Kraft, Martin Bertau, Nicole Bechmann, Kaomei Guan, Stefan R. Bornstein, Alona Voronkina, Andriy Fursov, Magdalena Bejger, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Marek Figlerowicz, Oleg Pokrovsky, Teofil Jesionowski, Hermann Ehrlich
Published 2019-10-01