N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages

by Ronald Sluyter, Kara L. Vine
Published 2016-01-01

<i>N</i>-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

by Lisa Belfiore, Darren N. Saunders, Marie Ranson, Kara L. Vine
Published 2020-07-01

Improving the Delivery of SOD1 Antisense Oligonucleotides to Motor Neurons Using Calcium Phosphate-Lipid Nanoparticles

by Liyu Chen, Liyu Chen, Clare Watson, Clare Watson, Marco Morsch, Nicholas J. Cole, Roger S. Chung, Darren N. Saunders, Justin J. Yerbury, Kara L. Vine, Kara L. Vine
Published 2017-08-01

N-alkylated isatins evade P-gp mediated efflux and retain potency in MDR cancer cell lines

by Kara L. Vine, Lisa Belfiore, Luke Jones, Julie M. Locke, Samantha Wade, Elahe Minaei, Marie Ranson
Published 2016-01-01

Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS

by Natalie E. Farrawell, Luke McAlary, Jeremy S. Lum, Christen G. Chisholm, Sadaf T. Warraich, Ian P. Blair, Kara L. Vine, Darren N. Saunders, Justin J. Yerbury
Published 2020-11-01

N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitr...

by Bryce Keenan, Rocio K. Finol-Urdaneta, Ashleigh Hope, John B. Bremner, Maria Kavallaris, Daniel Lucena-Agell, María Ángela Oliva, Jose Fernando Díaz, Kara L. Vine
Published 2020-05-01

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background

by Jeremy S. Lum, Mikayla L. Brown, Natalie E. Farrawell, Luke McAlary, Diane Ly, Christen G. Chisholm, Josh Snow, Kara L. Vine, Tim Karl, Fabian Kreilaus, Lachlan E. McInnes, Sara Nikseresht, Paul S. Donnelly, Peter J. Crouch, Justin J. Yerbury
Published 2021-09-01