A modified protocol for successful miRNA profiling in human precision-cut lung slices (PCLS)

by Monika Niehof, Stella Marie Reamon-Buettner, Olga Danov, Tanja Hansen, Katherina Sewald
Published 2021-07-01

Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo

by Olga Danov, Lisa Lasswitz, Helena Obernolte, Christina Hesse, Armin Braun, Sabine Wronski, Katherina Sewald
Published 2019-10-01

Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini^® Resulting in Balanced Immune Response to Rhinovirus Infection...

by Stella Marie Reamon-Buettner, Monika Niehof, Natalie Hirth, Olga Danov, Helena Obernolte, Armin Braun, Jürgen Warnecke, Katherina Sewald, Sabine Wronski
Published 2019-05-01

The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue

by Melissa Zimniak, Luisa Kirschner, Helen Hilpert, Nina Geiger, Olga Danov, Heike Oberwinkler, Maria Steinke, Katherina Sewald, Jürgen Seibel, Jochen Bodem
Published 2021-03-01

Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique.

by Vanessa Neuhaus, Katharina Schwarz, Anna Klee, Sophie Seehase, Christine Förster, Olaf Pfennig, Danny Jonigk, Hans-Gerd Fieguth, Wolfgang Koch, Gregor Warnecke, Vidadi Yusibov, Katherina Sewald, Armin Braun
Published 2013-01-01

Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells

by Friederike Philipp, Anton Selich, Michael Rothe, Dirk Hoffmann, Susanne Rittinghausen, Michael A. Morgan, Denise Klatt, Silke Glage, Stefan Lienenklaus, Vanessa Neuhaus, Katherina Sewald, Armin Braun, Axel Schambach
Published 2018-11-01

Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1

by Olga Danov, Martin Wolff, Sabine Bartel, Sabine Bartel, Sebastian Böhlen, Helena Obernolte, Sabine Wronski, Danny Jonigk, Barbara Hammer, Draginja Kovacevic, Sebastian Reuter, Sebastian Reuter, Susanne Krauss-Etschmann, Susanne Krauss-Etschmann, Katherina Sewald
Published 2020-11-01

Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality

by Vanessa Neuhaus, Dirk Schaudien, Tatiana Golovina, Ulla-Angela Temann, Carolann Thompson, Torsten Lippmann, Claus Bersch, Olaf Pfennig, Danny Jonigk, Peter Braubach, Hans-Gerd Fieguth, Gregor Warnecke, Vidadi Yusibov, Katherina Sewald, Armin Braun
Published 2017-05-01

LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing.

by Sophie Seehase, Hans-Dieter Lauenstein, Christina Schlumbohm, Simone Switalla, Vanessa Neuhaus, Christine Förster, Hans-Gerd Fieguth, Olaf Pfennig, Eberhard Fuchs, Franz-Josef Kaup, Martina Bleyer, Jens M Hohlfeld, Armin Braun, Katherina Sewald, Sascha Knauf
Published 2012-01-01

Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs.

by Olga Danov, Sharon Melissa Jiménez Delgado, Helena Obernolte, Sophie Seehase, Susann Dehmel, Peter Braubach, Hans-Gerd Fieguth, Gabriele Matschiner, Mary Fitzgerald, Danny Jonigk, Sascha Knauf, Olaf Pfennig, Gregor Warnecke, Judy Wichmann, Armin Braun, Katherina Sewald
Published 2018-01-01

Neurally mediated airway constriction in human and other species: a comparative study using precision-cut lung slices (PCLS).

by Marco Schlepütz, Annette D Rieg, Sophie Seehase, Jan Spillner, Alberto Perez-Bouza, Till Braunschweig, Thomas Schroeder, Marc Bernau, Verena Lambermont, Christina Schlumbohm, Katherina Sewald, Rüdiger Autschbach, Armin Braun, Boris W Kramer, Stefan Uhlig, Christian Martin
Published 2012-01-01

Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.

by Pawel Zmora, Paulina Molau-Blazejewska, Stephanie Bertram, Kerstin Walendy-Gnirß, Inga Nehlmeier, Anika Hartleib, Anna-Sophie Moldenhauer, Sebastian Konzok, Susann Dehmel, Katherina Sewald, Constantin Brinkmann, Christoph Curths, Sascha Knauf, Jens Gruber, Kerstin Mätz-Rensing, Franziska Dahlmann, Armin Braun, Stefan Pöhlmann
Published 2017-01-01

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

by Mania Ackermann, Henning Kempf, Miriam Hetzel, Christina Hesse, Anna Rafiei Hashtchin, Kerstin Brinkert, Juliane Wilhelmine Schott, Kathrin Haake, Mark Philipp Kühnel, Silke Glage, Constanca Figueiredo, Danny Jonigk, Katherina Sewald, Axel Schambach, Sabine Wronski, Thomas Moritz, Ulrich Martin, Robert Zweigerdt, Antje Munder, Nico Lachmann
Published 2018-11-01

Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors

by Kathrin Siebers, Bijan Fink, Anna Zakrzewicz, Alisa Agné, Katrin Richter, Sebastian Konzok, Andreas Hecker, Sven Zukunft, Mira Küllmar, Jochen Klein, J. Michael McIntosh, J. Michael McIntosh, J. Michael McIntosh, Thomas Timm, Katherina Sewald, Winfried Padberg, Nupur Aggarwal, Walee Chamulitrat, Sentot Santoso, Wendy Xia, Sabina Janciauskiene, Veronika Grau
Published 2018-04-01