TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps

by Jason Yi, Lakshmi Balagopalan, Tiffany Nguyen, Katherine M. McIntire, Lawrence E. Samelson
Published 2019-01-01

Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation

by Lakshmi Balagopalan, Jason Yi, Tiffany Nguyen, Katherine M. McIntire, Adam S. Harned, Kedar Narayan, Lawrence E. Samelson
Published 2018-05-01

Bypassing ubiquitination enables LAT recycling to the cell surface and enhanced signaling in T cells.

by Lakshmi Balagopalan, Hiba Malik, Katherine M McIntire, Joseph A Garvey, Tiffany Nguyen, Ana B Rodriguez-Peña, Lawrence E Samelson
Published 2020-01-01