Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment

by Seán Fitzgerald, Virginia Espina, Lance Liotta, Katherine M. Sheehan, Anthony O’Grady, Robert Cummins, Richard O’Kennedy, Elaine W. Kay, Gregor S. Kijanka
Published 2018-04-01

Development of a Novel Weighted Ranking Method for Immunohistochemical Quantification of a Heterogeneously Expressed Protein in Gastro-Esophageal Cancers

by Cathy E. Richards, Katherine M. Sheehan, Elaine W. Kay, Charlotta Hedner, David Borg, Joanna Fay, Anthony O’Grady, Arnold D. K. Hill, Karin Jirström, Ann M. Hopkins
Published 2021-03-01

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys.

by Alexandra M Ortiz, Diane G Carnathan, Joana Yu, Katherine M Sheehan, Peter Kim, Arnold Reynaldi, Thomas H Vanderford, Nichole R Klatt, Jason M Brenchley, Miles P Davenport, Guido Silvestri
Published 2016-01-01

Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings

by Astrid O. Leech, Sri HariKrishna Vellanki, Emily J. Rutherford, Aoife Keogh, Hanne Jahns, Lance Hudson, Norma O’Donovan, Siham Sabri, Bassam Abdulkarim, Katherine M. Sheehan, Elaine W. Kay, Leonie S. Young, Arnold D. K. Hill, Yvonne E. Smith, Ann M. Hopkins
Published 2018-11-01

Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer

by M. Janusz Mezynski, Angela M. Farrelly, Mattia Cremona, Aoife Carr, Clare Morgan, Julie Workman, Paul Armstrong, Jennifer McAuley, Stephen Madden, Joanna Fay, Katherine M. Sheehan, Elaine W. Kay, Ciara Holohan, Yasir Elamin, Shereen Rafee, Patrick G. Morris, Oscar Breathnach, Liam Grogan, Bryan T. Hennessy, Sinead Toomey
Published 2021-05-01

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted ther...

by Sinead Toomey, Alexander J. Eustace, Joanna Fay, Katherine M. Sheehan, Aoife Carr, Malgorzata Milewska, Stephen F. Madden, Ausra Teiserskiene, Elaine W. Kay, Norma O’Donovan, William Gallagher, Liam Grogan, Oscar Breathnach, Janice Walshe, Catherine Kelly, Brian Moulton, M. John Kennedy, Guiseppe Gullo, Arnold D. Hill, Colm Power, Deirdre Duke, Niamh Hambly, John Crown, Bryan T. Hennessy
Published 2017-07-01

Genomic and Transcriptomic Characterisation of Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

by Sinead Toomey, Jillian Gunther, Aoife Carr, David C. Weksberg, Valentina Thomas, Manuela Salvucci, Orna Bacon, El-Masry Sherif, Joanna Fay, Elaine W. Kay, Katherine M. Sheehan, Deborah A. McNamara, Keith L Sanders, Geena Mathew, Oscar S. Breathnach, Liam Grogan, Patrick G. Morris, Wai C. Foo, Yi-Qian N. You, Jochen H. Prehn, Brian O’Neill, Sunil Krishnan, Bryan T. Hennessy, Simon J. Furney
Published 2020-07-01