CFTR Rescue in Intestinal Organoids with GLPG/ABBV-2737, ABBV/GLPG-2222 and ABBV/GLPG-2451 Triple Therapy

by Eyleen de Poel, Eyleen de Poel, Sacha Spelier, Sacha Spelier, Ricardo Korporaal, Ka Wai Lai, Sylvia F. Boj, Katja Conrath, Cornelis K. van der Ent, Jeffrey M. Beekman, Jeffrey M. Beekman
Published 2021-09-01

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.

by Benoît Stijlemans, Guy Caljon, Senthil Kumar A Natesan, Dirk Saerens, Katja Conrath, David Pérez-Morga, Jeremy N Skepper, Alexandros Nikolaou, Lea Brys, Etienne Pays, Stefan Magez, Mark C Field, Patrick De Baetselier, Serge Muyldermans
Published 2011-06-01

Identification of GLPG/ABBV-2737, a Novel Class of Corrector, Which Exerts Functional Synergy With Other CFTR Modulators

by Gert de Wilde, Maarten Gees, Sara Musch, Katleen Verdonck, Mia Jans, Anne-Sophie Wesse, Ashvani K. Singh, Tzyh-Chang Hwang, Thierry Christophe, Mathieu Pizzonero, Steven Van der Plas, Nicolas Desroy, Marlon Cowart, Pieter Stouten, Luc Nelles, Katja Conrath
Published 2019-05-01

Identification and Characterization of Novel CFTR Potentiators

by Maarten Gees, Sara Musch, Steven Van der Plas, Anne-Sophie Wesse, Ann Vandevelde, Katleen Verdonck, Oscar Mammoliti, Tzyh-Chang Hwang, Kathleen Sonck, Pieter Stouten, Andrew M. Swensen, Mia Jans, Jan Van der Schueren, Luc Nelles, Martin Andrews, Katja Conrath
Published 2018-10-01