Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis

by Jenna R. Karras, Carolyn A. Paisie, Kay Huebner
Published 2014-06-01

Impact of FHIT loss on the translation of cancer-associated mRNAs

by Daniel L. Kiss, William Baez, Kay Huebner, Ralf Bundschuh, Daniel R. Schoenberg
Published 2017-12-01

Loss of fragile histidine triad (Fhit) protein expression alters the translation of cancer-associated mRNAs

by Daniel L. Kiss, William D. Baez, Kay Huebner, Ralf Bundschuh, Daniel R. Schoenberg
Published 2018-03-01

Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer

by Alessandra Drusco, Yuri Pekarsky, Stefan Costinean, Anna Antenucci, Laura Conti, Stefano Volinia, Rami I. Aqeilan, Kay Huebner, Nicola Zanesi
Published 2011-01-01

FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs.

by Sung-Suk Suh, Ji Young Yoo, Ri Cui, Balveen Kaur, Kay Huebner, Taek-Kyun Lee, Rami I Aqeilan, Carlo M Croce
Published 2014-10-01

Initiation of genome instability and preneoplastic processes through loss of Fhit expression.

by Joshua C Saldivar, Satoshi Miuma, Jessica Bene, Seyed Ali Hosseini, Hidetaka Shibata, Jin Sun, Linda J Wheeler, Christopher K Mathews, Kay Huebner
Published 2012-01-01

Integrated microRNA and mRNA signatures associated with survival in triple negative breast cancer.

by Luciano Cascione, Pierluigi Gasparini, Francesca Lovat, Stefania Carasi, Alfredo Pulvirenti, Alfredo Ferro, Hansjuerg Alder, Gang He, Andrea Vecchione, Carlo M Croce, Charles L Shapiro, Kay Huebner
Published 2013-01-01

Fhit deficiency-induced global genome instability promotes mutation and clonal expansion.

by Satoshi Miuma, Joshua C Saldivar, Jenna R Karras, Catherine E Waters, Carolyn A Paisie, Yao Wang, Victor Jin, Jin Sun, Teresa Druck, Jie Zhang, Kay Huebner
Published 2013-01-01

Androgen receptor status is a prognostic marker in non-basal triple negative breast cancers and determines novel therapeutic options.

by Pierluigi Gasparini, Matteo Fassan, Luciano Cascione, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carolyn Paisie, Francesca Lovat, Carl Morrison, Jianying Zhang, Aldo Scarpa, Carlo M Croce, Charles L Shapiro, Kay Huebner
Published 2014-01-01