Ischemia-related subcellular redistribution of sodium channels enhances the proarrhythmic effect of class I antiarrhythmic drugs: a simulation study.

by Kunichika Tsumoto, Takashi Ashihara, Ryo Haraguchi, Kazuo Nakazawa, Yoshihisa Kurachi
Published 2014-01-01

A kinematic approach for efficient and robust simulation of the cardiac beating motion.

by Takashi Ijiri, Takashi Ashihara, Nobuyuki Umetani, Takeo Igarashi, Ryo Haraguchi, Hideo Yokota, Kazuo Nakazawa
Published 2012-01-01

Not all rotors, effective ablation targets for nonparoxysmal atrial fibrillation, are included in areas suggested by conventional indirect indicators of atrial fibrillation drivers...

by Kensuke Sakata, Yusuke Okuyama, Tomoya Ozawa, Ryo Haraguchi, Kazuo Nakazawa, Takeshi Tsuchiya, Minoru Horie, Takashi Ashihara
Published 2018-04-01

Importance of gradients in membrane properties and electrical coupling in sinoatrial node pacing.

by Shin Inada, Henggui Zhang, James O Tellez, Nitaro Shibata, Kazuo Nakazawa, Kaichiro Kamiya, Itsuo Kodama, Kazuyuki Mitsui, Halina Dobrzynski, Mark R Boyett, Haruo Honjo
Published 2014-01-01

Pharmacological Blockade of IKs Destabilizes Spiral-Wave Reentry Under β-Adrenergic Stimulation in Favor of Its Early Termination

by Sara Kato, Haruo Honjo, Yoshio Takemoto, Hiroki Takanari, Tomoyuki Suzuki, Yusuke Okuno, Tobias Opthof, Ichiro Sakuma, Shin Inada, Kazuo Nakazawa, Takashi Ashihara, Itsuo Kodama, Kaichiro Kamiya
Published 2012-01-01

Transplantation of Mesenchymal Stem Cells Improves Atrioventricular Conduction in a Rat Model of Complete Atrioventricular Block

by Miki Yokokawa, Shunsuke Ohnishi M.D., Ph.D., Hatsue Ishibashi-Ueda, Hiroaki Obata, Kentaro Otani, Yoshinori Miyahara, Koichi Tanaka, Wataru Shimizu, Kazuo Nakazawa, Kenji Kangawa, Shiro Kamakura, Soichiro Kitamura, Noritoshi Nagaya
Published 2008-10-01

Prevalence and prognosis of patients with lone and paroxysmal atrial tachyarrhythmias showing Brugada-type electrocardiograms after class IC antiarrhythmic drug administration but...

by Atsuko Abe, MD, Tadashi Fujino, MD, Shunji Fukunaga, MD, Hitomi Yuzawa, MD, Hideyuki Sato, MD, Takeya Suzuki, MD, Kenzaburo Kobayashi, MD, Yoshifumi Okano, MD, Kentaro Nakamura, MD, Satoru Yusu, MD, Hideaki Yoshino, MD, Takashi Ashihara, MD, Kazuo Nakazawa, MD, Takanori Ikeda, MD
Published 2013-04-01

Simulation of ventricular rate control during atrial fibrillation using ionic channel blockers

by Shin Inada, PhD, Nitaro Shibata, MD, PhD, Michiaki Iwata, PhD, Ryo Haraguchi, PhD, Takashi Ashihara MD, PhD, Takanori Ikeda, MD, PhD, Kazuyuki Mitsui, PhD, Halina Dobrzynski, PhD, Mark R. Boyett, PhD, Kazuo Nakazawa, PhD
Published 2017-08-01

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy

by Fernande Freyermuth, Frédérique Rau, Yosuke Kokunai, Thomas Linke, Chantal Sellier, Masayuki Nakamori, Yoshihiro Kino, Ludovic Arandel, Arnaud Jollet, Christelle Thibault, Muriel Philipps, Serge Vicaire, Bernard Jost, Bjarne Udd, John W. Day, Denis Duboc, Karim Wahbi, Tsuyoshi Matsumura, Harutoshi Fujimura, Hideki Mochizuki, François Deryckere, Takashi Kimura, Nobuyuki Nukina, Shoichi Ishiura, Vincent Lacroix, Amandine Campan-Fournier, Vincent Navratil, Emilie Chautard, Didier Auboeuf, Minoru Horie, Keiji Imoto, Kuang-Yung Lee, Maurice S. Swanson, Adolfo Lopez de Munain, Shin Inada, Hideki Itoh, Kazuo Nakazawa, Takashi Ashihara, Eric Wang, Thomas Zimmer, Denis Furling, Masanori P. Takahashi, Nicolas Charlet-Berguerand
Published 2016-04-01