A universal molecular prognostic score for gastrointestinal tumors

by Hideyuki Shimizu, Keiichi I. Nakayama
Published 2021-02-01

A 23 gene–based molecular prognostic score precisely predicts overall survival of breast cancer patientsResearch in context

by Hideyuki Shimizu, Keiichi I. Nakayama
Published 2019-08-01

F-Box Proteins and Cancer

by Kanae Yumimoto, Yuhei Yamauchi, Keiichi I. Nakayama
Published 2020-05-01

Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages

by Hirokazu Nakatsumi, Masaki Matsumoto, Keiichi I. Nakayama
Published 2017-11-01

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

by Yoshiharu Muto, Masaaki Nishiyama, Akihiro Nita, Toshiro Moroishi, Keiichi I. Nakayama
Published 2017-07-01

Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development

by Susanne Laukoter, Robert Beattie, Florian M. Pauler, Nicole Amberg, Keiichi I. Nakayama, Simon Hippenmeyer
Published 2020-01-01

The autism-associated protein CHD8 is required for cerebellar development and motor function

by Atsuki Kawamura, Yuta Katayama, Wataru Kakegawa, Daisuke Ino, Masaaki Nishiyama, Michisuke Yuzaki, Keiichi I. Nakayama
Published 2021-04-01

Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning

by Michiko Shirane, Hirotaka Shoji, Yutaka Hashimoto, Hiroyuki Katagiri, Shizuka Kobayashi, Toshiya Manabe, Tsuyoshi Miyakawa, Keiichi I. Nakayama
Published 2020-11-01

Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

by Stanislav M. Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I. Nakayama, Masaaki Nishiyama, Haruhiro Higashida
Published 2021-05-01

Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells

by Hiroyuki Hosokawa, Tomoaki Tanaka, Yusuke Endo, Miki Kato, Kenta Shinoda, Akane Suzuki, Shinichiro Motohashi, Masaki Matsumoto, Keiichi I. Nakayama, Toshinori Nakayama
Published 2016-04-01

An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver

by Fumiko Matsuzaki, Shinsuke Uda, Yukiyo Yamauchi, Masaki Matsumoto, Tomoyoshi Soga, Kazumitsu Maehara, Yasuyuki Ohkawa, Keiichi I. Nakayama, Shinya Kuroda, Hiroyuki Kubota
Published 2021-08-01

A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer

by Manabu Kodama, Kiyotaka Oshikawa, Hideyuki Shimizu, Susumu Yoshioka, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Chisa Tateishi, Takeshi Tomonaga, Masaki Matsumoto, Keiichi I. Nakayama
Published 2020-03-01

Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

by Michiko Shirane, Mariko Wada, Keiko Morita, Nahoki Hayashi, Reina Kunimatsu, Yuki Matsumoto, Fumiko Matsuzaki, Hirokazu Nakatsumi, Keisuke Ohta, Yasushi Tamura, Keiichi I. Nakayama
Published 2020-09-01

Inhibiting Skp2 E3 Ligase Suppresses Bleomycin-Induced Pulmonary Fibrosis

by Masashi Mikamo, Kyoko Kitagawa, Satoshi Sakai, Chiharu Uchida, Tatsuya Ohhata, Koji Nishimoto, Hiroyuki Niida, Sayuri Suzuki, Keiichi I. Nakayama, Naoki Inui, Takafumi Suda, Masatoshi Kitagawa
Published 2018-02-01

The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression

by Tadashi Nakagawa, Satoko Hattori, Risa Nobuta, Ryuichi Kimura, Makiko Nakagawa, Masaki Matsumoto, Yuko Nagasawa, Ryo Funayama, Tsuyoshi Miyakawa, Toshifumi Inada, Noriko Osumi, Keiichi I. Nakayama, Keiko Nakayama
Published 2020-04-01

The amelioration of renal damage in Skp2-deficient mice canceled by p27 Kip1 deficiency in Skp2-/- p27-/- mice.

by Sayuri Suzuki, Hirotaka Fukasawa, Taro Misaki, Akashi Togawa, Naro Ohashi, Kyoko Kitagawa, Yojiro Kotake, Ning Liu, Hiroyuki Niida, Keiko Nakayama, Keiichi I Nakayama, Tatsuo Yamamoto, Masatoshi Kitagawa
Published 2012-01-01

Structural basis for the assembly of the Ragulator-Rag GTPase complex

by Ryo Yonehara, Shigeyuki Nada, Tomokazu Nakai, Masahiro Nakai, Ayaka Kitamura, Akira Ogawa, Hirokazu Nakatsumi, Keiichi I. Nakayama, Songling Li, Daron M. Standley, Eiki Yamashita, Atsushi Nakagawa, Masato Okada
Published 2017-11-01

SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction

by Hidefumi Fukushima, Akinobu Matsumoto, Hiroyuki Inuzuka, Bo Zhai, Alan W. Lau, Lixin Wan, Daming Gao, Shavali Shaik, Min Yuan, Steven P. Gygi, Eijiro Jimi, John M. Asara, Keiko Nakayama, Keiichi I. Nakayama, Wenyi Wei
Published 2012-05-01

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis

by Tadasuke Tsukiyama, Juqi Zou, Jihoon Kim, Shohei Ogamino, Yuki Shino, Takamasa Masuda, Alessandra Merenda, Masaki Matsumoto, Yoichiro Fujioka, Tomonori Hirose, Sayuri Terai, Hidehisa Takahashi, Tohru Ishitani, Keiichi I. Nakayama, Yusuke Ohba, Bon-Kyoung Koo, Shigetsugu Hatakeyama
Published 2020-09-01

A ubiquitin-like protein encoded by the “noncoding” RNA TINCR promotes keratinocyte proliferation and wound healing

by Akihiro Nita, Akinobu Matsumoto, Ronghao Tang, Chisa Shiraishi, Kazuya Ichihara, Daisuke Saito, Mikita Suyama, Tomoharu Yasuda, Gaku Tsuji, Masutaka Furue, Bumpei Katayama, Toshiyuki Ozawa, Teruasa Murata, Teruki Dainichi, Kenji Kabashima, Atsushi Hatano, Masaki Matsumoto, Keiichi I. Nakayama
Published 2021-08-01