The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage.

by Melissa C Srougi, Keith Burridge
Published 2011-02-01

Regulation of Rho Family GTPases by Cell-Cell and Cell-Matrix Adhesion

by WILLIAM T. ARTHUR, NICOLE K. NOREN, KEITH BURRIDGE
Published 2002-01-01

Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif.

by Amir Aghajanian, Erika S Wittchen, Sharon L Campbell, Keith Burridge
Published 2009-11-01

Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation.

by Shijun Wang, Canhong Cao, Zhongming Chen, Vytas Bankaitis, Eleni Tzima, Nader Sheibani, Keith Burridge
Published 2012-01-01

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals.

by Adi D Dubash, Christophe Guilluy, Melissa C Srougi, Etienne Boulter, Keith Burridge, Rafael García-Mata
Published 2011-02-01

The role of endothelial MERTK during the inflammatory response in lungs.

by Yitong Li, Erika S Wittchen, Elizabeth Monaghan-Benson, Cornelia Hahn, H Shelton Earp, Claire M Doerschuk, Keith Burridge
Published 2019-01-01

Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction.

by Hyunna T Lee, Lisa Sharek, E Timothy O'Brien, Fabio L Urbina, Stephanie L Gupton, Richard Superfine, Keith Burridge, Sharon L Campbell
Published 2019-01-01

Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells

by Alejandra Valdivia, Areli Cárdenas, Marianne Brenet, Horacio Maldonado, Milene Kong, Jorge Díaz, Keith Burridge, Pascal Schneider, Alejandra San Martín, Rafael García-Mata, Andrew F. G. Quest, Lisette Leyton
Published 2020-08-01

Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration.

by Zaozao Chen, Elizabeth Lessey, Matthew E Berginski, Li Cao, Jonathan Li, Xavier Trepat, Michelle Itano, Shawn M Gomez, Maryna Kapustina, Cai Huang, Keith Burridge, George Truskey, Ken Jacobson
Published 2013-01-01

The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis.

by Thomas Samson, Jaap D van Buul, Jeffrey Kroon, Christopher Welch, Erik N Bakker, Hanke L Matlung, Timo K van den Berg, Lisa Sharek, Claire Doerschuk, Klaus Hahn, Keith Burridge
Published 2013-01-01