A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells

by Katherine L. Misuraca, Guo Hu, Kelly L. Barton, Alexander Chung, Oren J. Becher
Published 2016-01-01

PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma.

by Kelly L Barton, Katherine Misuraca, Francisco Cordero, Elena Dobrikova, Hooney D Min, Matthias Gromeier, David G Kirsch, Oren J Becher
Published 2013-01-01

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models.

by Tammy Hennika, Guo Hu, Nagore G Olaciregui, Kelly L Barton, Anahid Ehteda, Arjanna Chitranjan, Cecilia Chang, Andrew J Gifford, Maria Tsoli, David S Ziegler, Angel M Carcaboso, Oren J Becher
Published 2017-01-01

A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent.

by Kyle G Halvorson, Kelly L Barton, Kristin Schroeder, Katherine L Misuraca, Christine Hoeman, Alex Chung, Donna M Crabtree, Francisco J Cordero, Raj Singh, Ivan Spasojevic, Noah Berlow, Ranadip Pal, Oren J Becher
Published 2015-01-01