Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumors

by Omkar Singh, Drew Pratt, Kenneth Aldape
Published 2021-09-01

Precision histology: how deep learning is poised to revitalize histomorphology for personalized cancer care

by Ugljesa Djuric, Gelareh Zadeh, Kenneth Aldape, Phedias Diamandis
Published 2017-06-01

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

by Sanju Sinha, Kuoyuan Cheng, Alejandro A Schäffer, Kenneth Aldape, Eyal Schiff, Eytan Ruppin
Published 2020-07-01

Aggressive chemotherapy aimed at obviating radiation in two very young infants with disseminated anaplastic ependymoma

by Maria Carter-Febres, Emily A. Sloan, Melike Pekmezci, Angelica R. Putnam, Luke Linscott, Samuel Cheshier, Kenneth Aldape, Carol S. Bruggers
Published 2021-09-01

TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy

by Qingxia Wei, Olivia Singh, Can Ekinci, Jaspreet Gill, Mira Li, Yasin Mamatjan, Shirin Karimi, Severa Bunda, Sheila Mansouri, Kenneth Aldape, Gelareh Zadeh
Published 2021-04-01

Diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma

by Drew Pratt, Martha Quezado, Zied Abdullaev, Debra Hawes, Fusheng Yang, Hugh J. L. Garton, Alexander R. Judkins, Rajen Mody, Arul Chinnaiyan, Kenneth Aldape, Carl Koschmann, Sriram Venneti
Published 2020-03-01

High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma

by Mark Raffeld, Zied Abdullaev, Svetlana D. Pack, Liqiang Xi, Sushma Nagaraj, Nicole Briceno, Elizabeth Vera, Stefania Pittaluga, Osorio Lopes Abath Neto, Martha Quezado, Kenneth Aldape, Terri S. Armstrong, Mark R. Gilbert
Published 2020-07-01

CIC protein instability contributes to tumorigenesis in glioblastoma

by Severa Bunda, Pardeep Heir, Julie Metcalf, Annie Si Cong Li, Sameer Agnihotri, Stefan Pusch, Mamatjan Yasin, Mira Li, Kelly Burrell, Sheila Mansouri, Olivia Singh, Mark Wilson, Amir Alamsahebpour, Romina Nejad, Bethany Choi, David Kim, Andreas von Deimling, Gelareh Zadeh, Kenneth Aldape
Published 2019-02-01

Case Report: Single-Cell Transcriptomic Analysis of an Anaplastic Oligodendroglioma Post Immunotherapy

by Guangyang Yu, Madison K. Butler, Abdalla Abdelmaksoud, Ying Pang, Yu-Ting Su, Zachary Rae, Kimia Dadkhah, Michael C. Kelly, Young K. Song, Jun S. Wei, Masaki Terabe, Ramya Atony, Kelly Mentges, Brett J. Theeler, Marta Penas-Prado, John Butman, Kevin Camphausen, Kareem A. Zaghloul, Edjah Nduom, Martha Quezado, Kenneth Aldape, Terri S. Armstrong, Mark R. Gilbert, James L. Gulley, Javed Khan, Jing Wu
Published 2021-01-01