Will the real bile acid sulfotransferase please stand up? Identification of Sult2a8 as a major hepatic bile acid sulfonating enzyme in mice1

by Paul A. Dawson, Kenneth D.R. Setchell
Published 2017-06-01

Long-Term Cholic Acid Therapy in Zellweger Spectrum Disorders

by James E. Heubi, Kenneth D.R. Setchell, Kevin E. Bove
Published 2018-06-01

Automated in vivo platform for the discovery of functional food treatments of hypercholesterolemia.

by Robert M Littleton, Kevin J Haworth, Hong Tang, Kenneth D R Setchell, Sandra Nelson, Jay R Hove
Published 2013-01-01

Successful treatment of infantile oxysterol 7α-hydroxylase deficiency with oral chenodeoxycholic acid

by Yun-Ping Tang, Jing-Yu Gong, Kenneth D. R. Setchell, Wujuan Zhang, Jing Zhao, Jian-She Wang
Published 2021-04-01

Substrate compositional variation with tissue/region and Gba1 mutations in mouse models--implications for Gaucher disease.

by Ying Sun, Wujuan Zhang, You-Hai Xu, Brian Quinn, Nupur Dasgupta, Benjamin Liou, Kenneth D R Setchell, Gregory A Grabowski
Published 2013-01-01

Ubiquitous transgene expression of the glucosylceramide-synthesizing enzyme accelerates glucosylceramide accumulation and storage cells in a Gaucher disease mouse model.

by Sonya Barnes, You-Hai Xu, Wujuan Zhang, Benjamin Liou, Kenneth D R Setchell, Liming Bao, Gregory A Grabowski, Ying Sun
Published 2014-01-01

Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease

by Yanyan Peng, Benjamin Liou, Yi Lin, Venette Fannin, Wujuan Zhang, Ricardo A. Feldman, Kenneth D. R. Setchell, Gregory A. Grabowski, Ying Sun
Published 2021-09-01

Separation of micelles and vesicles within lumenal aspirates from healthy humans: solubilization of cholesterol after a meal

by Lihang Yao, James E. Heubi, Donna D. Buckley, Humberto Fierra, Kenneth D.R. Setchell, Norman A. Granholm, Patrick Tso, David Y. Hui, Laura A. Woollett
Published 2002-04-01

Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse.

by Ying Sun, Huimin Ran, Benjamin Liou, Brian Quinn, Matt Zamzow, Wujuan Zhang, Jacek Bielawski, Kazuyuki Kitatani, Kenneth D R Setchell, Yusuf A Hannun, Gregory A Grabowski
Published 2011-04-01

Genetic spectrum and clinical characteristics of 3β-hydroxy-Δ5-C27-steroid oxidoreductase (HSD3B7) deficiency in China

by Jing Zhao, Kenneth D. R. Setchell, Ying Gong, Yinghua Sun, Ping Zhang, James E. Heubi, Lingjuan Fang, Yi Lu, Xinbao Xie, Jingyu Gong, Jian-She Wang
Published 2021-10-01

Properties of neurons derived from induced pluripotent stem cells of Gaucher disease type 2 patient fibroblasts: potential role in neuropathology.

by Ying Sun, Jane Florer, Christopher N Mayhew, Zhanfeng Jia, Zhiying Zhao, Kui Xu, Huimin Ran, Benjamin Liou, Wujuan Zhang, Kenneth D R Setchell, Jianguo Gu, Gregory A Grabowski
Published 2015-01-01

Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease

by Jinlong Jian, Qing-Yun Tian, Aubryanna Hettinghouse, Shuai Zhao, Helen Liu, Jianlu Wei, Gabriele Grunig, Wujuan Zhang, Kenneth D.R. Setchell, Ying Sun, Herman S. Overkleeft, Gerald L. Chan, Chuan-ju Liu
Published 2016-11-01

Study of Environmental Enteropathy and Malnutrition (SEEM) in Pakistan: protocols for biopsy based biomarker discovery and validation

by Najeeha T. Iqbal, Sana Syed, Kamran Sadiq, Marium N. Khan, Junaid Iqbal, Jennie Z. Ma, Fayaz Umrani, Sheraz Ahmed, Elizabeth A. Maier, Lee A. Denson, Yael Haberman, Monica M. McNeal, Kenneth D. R. Setchell, Xueheng Zhao, Shahida Qureshi, Lanlan Shen, Christopher A. Moskaluk, Ta-Chiang Liu, Omer Yilmaz, Donald E. Brown, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Sean R. Moore, S. Asad Ali
Published 2019-07-01