JNK Signaling in Stem Cell Self-Renewal and Differentiation

by Takashi Semba, Rachel Sammons, Xiaoping Wang, Xuemei Xie, Kevin N. Dalby, Naoto T. Ueno
Published 2020-04-01

Using docking and alchemical free energy perturbation to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis

by Qiantao eWang, Ramakrishna eEdupuganti, Clint D. J. Tavares, Kevin N. Dalby, Pengyu eRen
Published 2015-03-01

The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.

by Sergio Coffa, Maya Breitman, Susan M Hanson, Kari Callaway, Seunghyi Kook, Kevin N Dalby, Vsevolod V Gurevich
Published 2011-01-01

A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach.

by Sunbae Lee, Mangalika Warthaka, Chunli Yan, Tamer S Kaoud, Andrea Piserchio, Ranajeet Ghose, Pengyu Ren, Kevin N Dalby
Published 2011-04-01

Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer.

by Ibrahim Tekedereli, S Neslihan Alpay, Clint D J Tavares, Zehra E Cobanoglu, Tamer S Kaoud, Ibrahim Sahin, Anil K Sood, Gabriel Lopez-Berestein, Kevin N Dalby, Bulent Ozpolat
Published 2012-01-01

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding

by Hou-Fu Guo, Chi-Lin Tsai, Masahiko Terajima, Xiaochao Tan, Priyam Banerjee, Mitchell D. Miller, Xin Liu, Jiang Yu, Jovita Byemerwa, Sarah Alvarado, Tamer S. Kaoud, Kevin N. Dalby, Neus Bota-Rabassedas, Yulong Chen, Mitsuo Yamauchi, John A. Tainer, George N. Phillips, Jonathan M. Kurie
Published 2018-02-01

Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding

by Hou-Fu Guo, Chi-Lin Tsai, Masahiko Terajima, Xiaochao Tan, Priyam Banerjee, Mitchell D. Miller, Xin Liu, Jiang Yu, Jovita Byemerwa, Sarah Alvarado, Tamer S. Kaoud, Kevin N. Dalby, Neus Bota-Rabassedas, Yulong Chen, Mitsuo Yamauchi, John A. Tainer, George N. Phillips, Jonathan M. Kurie
Published 2018-07-01

Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

by Tamer S. Kaoud, William H. Johnson, Nancy D. Ebelt, Andrea Piserchio, Diana Zamora-Olivares, Sabrina X. Van Ravenstein, Jacey R. Pridgen, Ramakrishna Edupuganti, Rachel Sammons, Micael Cano, Mangalika Warthaka, Matthew Harger, Clint D. J. Tavares, Jihyun Park, Mohamed F. Radwan, Pengyu Ren, Eric V. Anslyn, Kenneth Y. Tsai, Ranajeet Ghose, Kevin N. Dalby
Published 2019-11-01

A collagen glucosyltransferase drives lung adenocarcinoma progression in mice

by Hou-Fu Guo, Neus Bota-Rabassedas, Masahiko Terajima, B. Leticia Rodriguez, Don L. Gibbons, Yulong Chen, Priyam Banerjee, Chi-Lin Tsai, Xiaochao Tan, Xin Liu, Jiang Yu, Michal Tokmina-Roszyk, Roma Stawikowska, Gregg B. Fields, Mitchell D. Miller, Xiaoyan Wang, Juhoon Lee, Kevin N. Dalby, Chad J. Creighton, George N. Phillips, John A. Tainer, Mitsuo Yamauchi, Jonathan M. Kurie
Published 2021-04-01

BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling

by Harina Vin, Sandra S Ojeda, Grace Ching, Marco L Leung, Vida Chitsazzadeh, David W Dwyer, Charles H Adelmann, Monica Restrepo, Kristen N Richards, Larissa R Stewart, Lili Du, Scarlett B Ferguson, Deepavali Chakravarti, Karin Ehrenreiter, Manuela Baccarini, Rosamaria Ruggieri, Jonathan L Curry, Kevin B Kim, Ana M Ciurea, Madeleine Duvic, Victor G Prieto, Stephen E Ullrich, Kevin N Dalby, Elsa R Flores, Kenneth Y Tsai
Published 2013-11-01