Kim Orth

Kim Orth is a microbiologist and biochemist. She is the Earl A. Forsythe chair in biomedical science and professor of molecular biology and biochemistry at UT Southwestern. She is a Howard Hughes Medical Institute investigator and a member of the National Academy of Sciences. Her research focuses on bacterial pathogenesis.

Kim Orth graduated from Texas A&M University in 1984 with a B.S. in biochemistry. She went to the UCLA School of Medicine for an M.S. in biological chemistry, and then to University of Texas Southwestern Medical Center for a PhD in biochemistry and molecular biology. Provided by Wikipedia
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  1. 1
    T3SS effector VopL inhibits the host ROS response, promoting the intracellular survival of Vibrio parahaemolyticus.
    by Marcela de Souza Santos, Dor Salomon, Kim Orth
    Published 2017-06-01
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    Article
  2. 2
    Vibrio parahaemolyticus type VI secretion system 1 is activated in marine conditions to target bacteria, and is differentially regulated from system 2.
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  3. 3
    Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration
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  4. 4
    A MAM7 peptide-based inhibitor of Staphylococcus aureus adhesion does not interfere with in vitro host cell function.
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  5. 5
    Fido, a novel AMPylation domain common to fic, doc, and AvrB.
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  6. 6
    The Biochemistry of Sensing: Enteric Pathogens Regulate Type III Secretion in Response to Environmental and Host Cues
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  7. 7
    High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
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  8. 8
    Vibrio type III effector VPA1380 is related to the cysteine protease domain of large bacterial toxins.
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  9. 9
    Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways.
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  10. 10
    Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus
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  11. 11
    Type III Effector VopC Mediates Invasion for Vibrio Species
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  12. 12
    Bile salt receptor complex activates a pathogenic type III secretion system
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  13. 13
    Type VI Secretion System Toxins Horizontally Shared between Marine Bacteria.
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  14. 14
    A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis
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  15. 15
    Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation
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  16. 16
    Manipulation of IRE1-Dependent MAPK Signaling by a Vibrio Agonist-Antagonist Effector Pair
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  17. 17
    Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex
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  18. 18
    Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress
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