Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region

by Ellen Sapp, Connor Seeley, Maria Iuliano, Elizabeth Weisman, Petr Vodicka, Marian DiFiglia, Kimberly B. Kegel-Gleason
Published 2020-07-01

Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington’s Disease Mouse Striatum

by Maria Iuliano, Connor Seeley, Ellen Sapp, Erin L. Jones, Callie Martin, Xueyi Li, Marian DiFiglia, Kimberly B. Kegel-Gleason
Published 2021-03-01

Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes.

by Adelaide Tousley, Maria Iuliano, Elizabeth Weisman, Ellen Sapp, Heather Richardson, Petr Vodicka, Jonathan Alexander, Neil Aronin, Marian DiFiglia, Kimberly B Kegel-Gleason
Published 2019-01-01

Lysosomal proteases are involved in generation of N-terminal huntingtin fragments

by Yun J. Kim, Ellen Sapp, Benjamin G. Cuiffo, Lindsay Sobin, Jennifer Yoder, Kimberly B. Kegel, Zheng-Hong Qin, Peter Detloff, Neil Aronin, Marian DiFiglia
Published 2006-05-01

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

by Xueyi Li, Ellen Sapp, Kathryn Chase, Laryssa A. Comer-Tierney, Nicholas Masso, Jonathan Alexander, Patrick Reeves, Kimberly B. Kegel, Antonio Valencia, Miguel Esteves, Neil Aronin, Marian DiFiglia
Published 2009-11-01