Pertussis toxin, an inhibitor of G(αi) PCR, inhibits bile acid- and cytokine-induced apoptosis in primary rat hepatocytes.

by Golnar Karimian, Manon Buist-Homan, Klaas Nico Faber, Han Moshage
Published 2012-01-01

Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1.

by Martijn O Hoeke, Janette Heegsma, Mark Hoekstra, Han Moshage, Klaas Nico Faber
Published 2014-01-01

Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.

by Golnar Karimian, Manon Buist-Homan, Bojana Mikus, Robert H Henning, Klaas Nico Faber, Han Moshage
Published 2012-01-01

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

by Daniela Parada Venegas, Daniela Parada Venegas, Marjorie K. De la Fuente, Glauben Landskron, María Julieta González, Rodrigo Quera, Gerard Dijkstra, Hermie J. M. Harmsen, Klaas Nico Faber, Klaas Nico Faber, Marcela A. Hermoso
Published 2019-03-01

Corrigendum: Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

by Daniela Parada Venegas, Daniela Parada Venegas, Marjorie K. De la Fuente, Glauben Landskron, María Julieta González, Rodrigo Quera, Gerard Dijkstra, Hermie J. M. Harmsen, Klaas Nico Faber, Klaas Nico Faber, Marcela A. Hermoso
Published 2019-06-01

Hormesis in Cholestatic Liver Disease; Preconditioning with Low Bile Acid Concentrations Protects against Bile Acid-Induced Toxicity.

by Esther M Verhaag, Manon Buist-Homan, Martijn Koehorst, Albert K Groen, Han Moshage, Klaas Nico Faber
Published 2016-01-01

Pirfenidone Inhibits Cell Proliferation and Collagen I Production of Primary Human Intestinal Fibroblasts

by Yingying Cui, Mengfan Zhang, Changsen Leng, Tjasso Blokzijl, Bernadien H. Jansen, Gerard Dijkstra, Klaas Nico Faber
Published 2020-03-01

Increased fecal calprotectin levels in Crohn's disease correlate with elevated serum Th1- and Th17-associated cytokines.

by Arno R Bourgonje, Julius Z H von Martels, Paul de Vos, Klaas Nico Faber, Gerard Dijkstra
Published 2018-01-01

Plasma Levels of Retinol Binding Protein 4 Relate to Large VLDL and Small LDL Particles in Subjects with and without Type 2 Diabetes

by Hanna Wessel, Ali Saeed, Janette Heegsma, Margery A. Connelly, Klaas Nico Faber, Robin P. F. Dullaart
Published 2019-10-01

Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD)

by Ali Saeed, Robin P. F. Dullaart, Tim C. M. A. Schreuder, Hans Blokzijl, Klaas Nico Faber
Published 2017-12-01

Assessing intestinal permeability in Crohn's disease patients using orally administered 52Cr-EDTA.

by Julius Z H von Martels, Arno R Bourgonje, Hermie J M Harmsen, Klaas Nico Faber, Gerard Dijkstra
Published 2019-01-01

Metformin protects rat hepatocytes against bile acid-induced apoptosis.

by Titia E Woudenberg-Vrenken, Laura Conde de la Rosa, Manon Buist-Homan, Klaas Nico Faber, Han Moshage
Published 2013-01-01

Hepatitis C Virus Proteins Core and NS5A Are Highly Sensitive to Oxidative Stress-Induced Degradation after eIF2α/ATF4 Pathway Activation

by W. Alfredo Ríos-Ocampo, María-Cristina Navas, Manon Buist-Homan, Klaas Nico Faber, Toos Daemen, Han Moshage
Published 2020-04-01

Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes against oxidative stress and endoplasmic reticulum stress

by W. Alfredo Ríos-Ocampo, Toos Daemen, Manon Buist-Homan, Klaas Nico Faber, María-Cristina Navas, Han Moshage
Published 2019-01-01

Hibernator-Derived Cells Show Superior Protection and Survival in Hypothermia Compared to Non-Hibernator Cells

by Koen D.W. Hendriks, Christian P. Joschko, Femke Hoogstra-Berends, Janette Heegsma, Klaas-Nico Faber, Robert H. Henning
Published 2020-03-01

Serum Free Thiols Are Superior to Fecal Calprotectin in Reflecting Endoscopic Disease Activity in Inflammatory Bowel Disease

by Arno R. Bourgonje, Ruben Y. Gabriëls, Martin H. de Borst, Marian L. C. Bulthuis, Klaas Nico Faber, Harry van Goor, Gerard Dijkstra
Published 2019-09-01

Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in HepatocytesSummary

by Ali Saeed, Paulina Bartuzi, Janette Heegsma, Daphne Dekker, Niels Kloosterhuis, Alain de Bruin, Johan W. Jonker, Bart van de Sluis, Klaas Nico Faber
Published 2021-01-01

Crohn’s Disease in Clinical Remission Is Marked by Systemic Oxidative Stress

by Arno R. Bourgonje, Julius Z. H. von Martels, Marian L. C. Bulthuis, Marco van Londen, Klaas Nico Faber, Gerard Dijkstra, Harry van Goor
Published 2019-04-01

A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease

by Arno R. Bourgonje, Julius Z. H. von Martels, Ruben Y. Gabriëls, Tjasso Blokzijl, Manon Buist-Homan, Janette Heegsma, Bernadien H. Jansen, Hendrik M. van Dullemen, Eleonora A. M. Festen, Rinze W. F. ter Steege, Marijn C. Visschedijk, Rinse K. Weersma, Paul de Vos, Klaas Nico Faber, Klaas Nico Faber, Gerard Dijkstra
Published 2019-11-01

Prevalence and determinants of non-alcoholic fatty liver disease in lifelines: A large Dutch population cohort.

by Eline H van den Berg, Marzyeh Amini, Tim C M A Schreuder, Robin P F Dullaart, Klaas Nico Faber, Behrooz Z Alizadeh, Hans Blokzijl
Published 2017-01-01