Reactive Carbonyl Species: A Missing Link in ROS Signaling

by Jun’ichi Mano, Md. Sanaullah Biswas, Koichi Sugimoto
Published 2019-09-01

Endothelin-1 Upregulates Activin Receptor-Like Kinase-1 Expression via Gi/RhoA/Sp-1/Rho Kinase Pathways in Human Pulmonary Arterial Endothelial Cells

by Koichi Sugimoto, Koichi Sugimoto, Tetsuro Yokokawa, Tetsuro Yokokawa, Tomofumi Misaka, Takashi Kaneshiro, Shinya Yamada, Akiomi Yoshihisa, Kazuhiko Nakazato, Yasuchika Takeishi
Published 2021-02-01

Receptor for advanced glycation end products - membrane type1 matrix metalloproteinase axis regulates tissue factor expression via RhoA and Rac1 activation in high-mobility group b...

by Koichi Sugimoto, Hiroshi Ohkawara, Yuichi Nakamura, Yoh Takuwa, Toshiyuki Ishibashi, Yasuchika Takeishi
Published 2014-01-01

Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells.

by Hiroshi Ohkawara, Toshiyuki Ishibashi, Koichi Sugimoto, Kazuhiko Ikeda, Kazuei Ogawa, Yasuchika Takeishi
Published 2014-01-01

High-fat diet attenuates the improvement of hypoxia-induced pulmonary hypertension in mice during reoxygenation

by Koichi Sugimoto, Tetsuro Yokokawa, Tomofumi Misaka, Takashi Kaneshiro, Akiomi Yoshihisa, Kazuhiko Nakazato, Yasuchika Takeishi
Published 2021-07-01

A Case of Severe Ganciclovir-Induced Encephalopathy

by Hikaru Sakamoto, Makito Hirano, Kazuhiro Nose, Shuichi Ueno, Takashi Oki, Koichi Sugimoto, Tsukasa Nishioka, Susumu Kusunoki, Yusaku Nakamura
Published 2013-10-01

Autoimmune disease mouse model exhibits pulmonary arterial hypertension.

by Koichi Sugimoto, Kazuhiko Nakazato, Akihiko Sato, Satoshi Suzuki, Akiomi Yoshihisa, Takeshi Machida, Shu-Ichi Saitoh, Hideharu Sekine, Yasuchika Takeishi
Published 2017-01-01

Associations between diabetes mellitus and pulmonary hypertension in chronic respiratory disease patients.

by Tomoko Takahashi, Akiomi Yoshihisa, Koichi Sugimoto, Tetsuro Yokokawa, Tomofumi Misaka, Takashi Kaneshiro, Masayoshi Oikawa, Atsushi Kobayashi, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi
Published 2018-01-01

Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome

by Tomofumi Misaka, Satoshi Suzuki, Nobuo Sakamoto, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Shu-ichi Saitoh, Tatsuya Sawamura, Toshiyuki Ishibashi, Yasuchika Takeishi
Published 2014-01-01

Predominance of Abdominal Visceral Adipose Tissue Reflects the Presence of Aortic Valve Calcification

by Masayoshi Oikawa, Takashi Owada, Hiroyuki Yamauchi, Tomofumi Misaka, Hirofumi Machii, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi
Published 2016-01-01

Epicardial Adipose Tissue Reflects the Presence of Coronary Artery Disease: Comparison with Abdominal Visceral Adipose Tissue

by Masayoshi Oikawa, Takashi Owada, Hiroyuki Yamauchi, Tomofumi Misaka, Hirofumi Machii, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi
Published 2015-01-01

Pulmonary Arterial Capacitance Predicts Cardiac Events in Pulmonary Hypertension Due to Left Heart Disease.

by Koichi Sugimoto, Akiomi Yoshihisa, Kazuhiko Nakazato, Yuichiro Jin, Satoshi Suzuki, Tetsuro Yokokawa, Tomofumi Misaka, Takayoshi Yamaki, Hiroyuki Kunii, Hitoshi Suzuki, Shu-Ichi Saitoh, Yasuchika Takeishi
Published 2016-01-01

Long-Term Effects and Prognosis in Acute Heart Failure Treated with Tolvaptan: The AVCMA Trial

by Satoshi Suzuki, Akiomi Yoshihisa, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Yukihiko Abe, Tomiyoshi Saito, Takayuki Ohwada, Hitoshi Suzuki, Shu-ichi Saitoh, Isao Kubota, Yasuchika Takeishi
Published 2014-01-01

Impact of sleep-disordered breathing on heart rate turbulence in heart failure patients.

by Akiomi Yoshihisa, Satoshi Suzuki, Mai Takiguchi, Takeshi Shimizu, Satoshi Abe, Takamasa Sato, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi
Published 2014-01-01

Establishment of a Therapeutic Anti-Pan HLA-Class II Monoclonal Antibody That Directly Induces Lymphoma Cell Death via Large Pore Formation.

by Shuji Matsuoka, Yasuyuki Ishii, Atsuhito Nakao, Masaaki Abe, Naomi Ohtsuji, Shuji Momose, Hui Jin, Hisashi Arase, Koichi Sugimoto, Yusuke Nakauchi, Hiroshi Masutani, Michiyuki Maeda, Hideo Yagita, Norio Komatsu, Okio Hino
Published 2016-01-01

Myeloproliferative neoplasm-driving Calr frameshift promotes the development of pulmonary hypertension in mice

by Keiji Minakawa, Tetsuro Yokokawa, Koki Ueda, Osamu Nakajima, Tomofumi Misaka, Yusuke Kimishima, Kento Wada, Yusuke Tomita, Saori Miura, Yuka Sato, Kosaku Mimura, Koichi Sugimoto, Kazuhiko Nakazato, Kenneth E. Nollet, Kazuei Ogawa, Takayuki Ikezoe, Yuko Hashimoto, Yasuchika Takeishi, Kazuhiko Ikeda
Published 2021-03-01

Liver dysfunction assessed by model for end-stage liver disease excluding INR (MELD-XI) scoring system predicts adverse prognosis in heart failure.

by Satoshi Abe, Akiomi Yoshihisa, Mai Takiguchi, Takeshi Shimizu, Yuichi Nakamura, Hiroyuki Yamauchi, Shoji Iwaya, Takashi Owada, Makiko Miyata, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi
Published 2014-01-01