A rigidifying salt-bridge favors the activity of thermophilic enzyme at high temperatures at the expense of low-temperature activity.

by Sonia Y Lam, Rachel C Y Yeung, Tsz-Ha Yu, Kong-Hung Sze, Kam-Bo Wong
Published 2011-03-01

Maize ribosome-inactivating protein uses Lys158-lys161 to interact with ribosomal protein P2 and the strength of interaction is correlated to the biological activities.

by Yuen-Ting Wong, Yiu-Ming Ng, Amanda Nga-Sze Mak, Kong-Hung Sze, Kam-Bo Wong, Pang-Chui Shaw
Published 2012-01-01

Mouse Spexin: (I) NMR Solution Structure, Docking Models for Receptor Binding, and Histological Expression at Tissue Level

by Matthew K. H. Wong, Mulan He, Kong Hung Sze, Tao Huang, Wendy K. W. Ko, Zhao-Xiang Bian, Anderson O. L. Wong
Published 2021-07-01

Structural analysis of the UBA domain of X-linked inhibitor of apoptosis protein reveals different surfaces for ubiquitin-binding and self-association.

by Man Kit Tse, Sin Kam Hui, Yinhua Yang, Si-Tao Yin, Hong-Yu Hu, Bing Zou, Benjamin Chun Yu Wong, Kong Hung Sze
Published 2011-01-01

A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile

by Bao-Zhong Zhang, Jianpiao Cai, Bin Yu, Yanhong Hua, Candy Choiyi Lau, Richard Yi-Tsun Tsun Kao, Kong-Hung Sze, Kwok-Yung Yuen, Jian-Dong Huang
Published 2016-10-01

A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2

by Hanjun Zhao, Kelvin K. W. To, Kong-Hung Sze, Timothy Tin-Mong Yung, Mingjie Bian, Hoiyan Lam, Man Lung Yeung, Cun Li, Hin Chu, Kwok-Yung Yuen
Published 2020-08-01

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication

by Bingpeng Yan, Hin Chu, Dong Yang, Kong-Hung Sze, Pok-Man Lai, Shuofeng Yuan, Huiping Shuai, Yixin Wang, Richard Yi-Tsun Kao, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Published 2019-01-01

Identification and characterization of GLDC as host susceptibility gene to severe influenza

by Jie Zhou, Dong Wang, Bosco Ho‐Yin Wong, Cun Li, Vincent Kwok‐Man Poon, Lei Wen, Xiaoyu Zhao, Man Chun Chiu, Xiaojuan Liu, Ziwei Ye, Shuofeng Yuan, Kong‐Hung Sze, Jasper Fuk‐Woo Chan, Hin Chu, Kelvin Kai‐Wang To, Kwok Yung Yuen
Published 2019-01-01

Metabolomic Profiling of Plasma from Melioidosis Patients Using UHPLC-QTOF MS Reveals Novel Biomarkers for Diagnosis

by Susanna K. P. Lau, Kim-Chung Lee, George C. S. Lo, Vanessa S. Y. Ding, Wang-Ngai Chow, Tony Y. H. Ke, Shirly O. T. Curreem, Kelvin K. W. To, Deborah T. Y. Ho, Siddharth Sridhar, Sally C. Y. Wong, Jasper F. W. Chan, Ivan F. N. Hung, Kong-Hung Sze, Ching-Wan Lam, Kwok-Yung Yuen, Patrick C. Y. Woo
Published 2016-02-01

Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei.

by Patrick C Y Woo, Susanna K P Lau, Candy C Y Lau, Edward T K Tung, Ken T K Chong, Fengjuan Yang, Hongmin Zhang, Raymond K C Lo, Jian-Pao Cai, Rex K H Au-Yeung, Wing-Fung Ng, Herman Tse, Samson S Y Wong, Simin Xu, Wai Hei Lam, Man-Kit Tse, Kong Hung Sze, Richard Y Kao, Neil E Reiner, Quan Hao, Kwok-Yung Yuen
Published 2016-08-01

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

by Shuofeng Yuan, Hin Chu, Jasper Fuk-Woo Chan, Zi-Wei Ye, Lei Wen, Bingpeng Yan, Pok-Man Lai, Kah-Meng Tee, Jingjing Huang, Dongdong Chen, Cun Li, Xiaoyu Zhao, Dong Yang, Man Chun Chiu, Cyril Yip, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Kong-Hung Sze, Jie Zhou, Ivy Hau-Yee Chan, Kin-Hang Kok, Kelvin Kai-Wang To, Richard Yi-Tsun Kao, Johnson Yiu-Nam Lau, Dong-Yan Jin, Stanley Perlman, Kwok-Yung Yuen
Published 2019-01-01