On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity

by Oleg Kovrov, Kristian Kølby Kristensen, Erika Larsson, Michael Ploug, Gunilla Olivecrona
Published 2019-04-01

ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain

by Kristian Kølby Kristensen, Katrine Zinck Leth-Espensen, Stephen G. Young, Michael Ploug
Published 2020-09-01

GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity

by Kristian Kølby Kristensen, Kristian Kølby Kristensen, Katrine Zinck Leth-Espensen, Katrine Zinck Leth-Espensen, Anni Kumari, Anni Kumari, Anne Louise Grønnemose, Anne Louise Grønnemose, Anne-Marie Lund-Winther, Anne-Marie Lund-Winther, Stephen G. Young, Stephen G. Young, Michael Ploug, Michael Ploug
Published 2021-07-01

The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding

by Simon Mysling, Kristian Kølby Kristensen, Mikael Larsson, Oleg Kovrov, André Bensadouen, Thomas JD Jørgensen, Gunilla Olivecrona, Stephen G Young, Michael Ploug
Published 2016-12-01

Evolution and Medical Significance of LU Domain−Containing Proteins

by Julie Maja Leth, Katrine Zinck Leth-Espensen, Kristian Kølby Kristensen, Anni Kumari, Anne-Marie Lund Winther, Stephen G. Young, Michael Ploug
Published 2019-06-01

Dynamic Na+/H+ exchanger 1 (NHE1) – calmodulin complexes of varying stoichiometry and structure regulate Ca2+-dependent NHE1 activation

by Lise M Sjøgaard-Frich, Andreas Prestel, Emilie S Pedersen, Marc Severin, Kristian Kølby Kristensen, Johan G Olsen, Birthe B Kragelund, Stine Falsig Pedersen
Published 2021-03-01

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain

by Simon Mysling, Kristian Kølby Kristensen, Mikael Larsson, Anne P Beigneux, Henrik Gårdsvoll, Loren G Fong, André Bensadouen, Thomas JD Jørgensen, Stephen G Young, Michael Ploug
Published 2016-01-01