Murine models for heart failure: Their creation and applicability to human still require critical and careful considerations

by Jessica Pfeiffer, Kristina Lorenz
Published 2021-06-01

How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency

by Tim Breitenbach, Kristina Lorenz, Thomas Dandekar
Published 2019-05-01

The A2B adenosine receptor in MDA-MB-231 breast cancer cells diminishes ERK1/2 phosphorylation by activation of MAPK-phosphatase-1.

by Marthe Koussémou, Kristina Lorenz, Karl-Norbert Klotz
Published 2018-01-01

Protective Effects of Thyroid Hormone Deprivation on Progression of Maladaptive Cardiac Hypertrophy and Heart Failure

by Helena Kerp, Georg Sebastian Hönes, Elen Tolstik, Judith Hönes-Wendland, Janina Gassen, Lars Christian Moeller, Kristina Lorenz, Kristina Lorenz, Dagmar Führer
Published 2021-07-01

Assessing the role of extracellular signal‐regulated kinases 1 and 2 in volume overload‐induced cardiac remodelling

by Svenja Jochmann, Manar Elkenani, Belal A. Mohamed, Eric Buchholz, Dawid Lbik, Lutz Binder, Kristina Lorenz, Ajay M. Shah, Gerd Hasenfuß, Karl Toischer, Moritz Schnelle
Published 2019-10-01

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis

by Tim Salinger, Kai Hu, Dan Liu, Scharoch Taleh, Sebastian Herrmann, Daniel Oder, Daniel Gensler, Jonas Müntze, Georg Ertl, Kristina Lorenz, Stefan Frantz, Frank Weidemann, Peter Nordbeck
Published 2018-01-01

Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue

by Alexandra Rhoden, Felix W. Friedrich, Theresa Brandt, Janice Raabe, Michaela Schweizer, Jana Meisterknecht, Ilka Wittig, Bärbel M. Ulmer, Birgit Klampe, June Uebeler, Angelika Piasecki, Kristina Lorenz, Thomas Eschenhagen, Arne Hansen, Friederike Cuello
Published 2021-05-01

Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression

by Michael Wagner, Mirna S. Sadek, Nataliya Dybkova, Fleur E. Mason, Johann Klehr, Rebecca Firneburg, Eleder Cachorro, Kurt Richter, Erik Klapproth, Stephan R. Kuenzel, Kristina Lorenz, Jordi Heijman, Dobromir Dobrev, Ali El-Armouche, Samuel Sossalla, Susanne Kämmerer
Published 2021-05-01

Biochemical and pathological changes result from mutated Caveolin-3 in muscle

by José Andrés González Coraspe, Joachim Weis, Mary E. Anderson, Ute Münchberg, Kristina Lorenz, Stephan Buchkremer, Stephanie Carr, René Peiman Zahedi, Eva Brauers, Hannah Michels, Yoshihide Sunada, Hanns Lochmüller, Kevin P. Campbell, Erik Freier, Denisa Hathazi, Andreas Roos
Published 2018-08-01

Modeling atrial fibrosis in vitro—Generation and characterization of a novel human atrial fibroblast cell line

by Stephan R. Künzel, Johanna S. E. Rausch, Charlotte Schäffer, Maximilian Hoffmann, Karolina Künzel, Erik Klapproth, Theresa Kant, Natalie Herzog, Jan‐Heiner Küpper, Kristina Lorenz, Svenja Dudek, Ramona Emig, Ursula Ravens, Eva A. Rog‐Zielinska, Rémi Peyronnet, Ali El‐Armouche
Published 2020-07-01

Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects

by Angela Tomasovic, Theresa Brand, Constanze Schanbacher, Sofia Kramer, Martin W. Hümmert, Patricio Godoy, Wolfgang Schmidt-Heck, Peter Nordbeck, Jonas Ludwig, Susanne Homann, Armin Wiegering, Timur Shaykhutdinov, Christoph Kratz, Ruth Knüchel, Hans-Konrad Müller-Hermelink, Andreas Rosenwald, Norbert Frey, Jutta Eichler, Dobromir Dobrev, Ali El-Armouche, Jan G. Hengstler, Oliver J. Müller, Karsten Hinrichs, Friederike Cuello, Alma Zernecke, Kristina Lorenz
Published 2020-04-01