Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation

by Phan Q. Duy, Phan Q. Duy, Wyatt B. David, Kristopher T. Kahle, Kristopher T. Kahle, Kristopher T. Kahle, Kristopher T. Kahle, Kristopher T. Kahle
Published 2019-11-01

Limitations of current GABA agonists in neonatal seizures: towards GABA modulation via the targeting of neuronal Cl- transport

by Arjun eKhanna, Brian Patrick Walcott, Kristopher T Kahle, Kristopher T Kahle
Published 2013-06-01

Recessive Inheritance of Congenital Hydrocephalus With Other Structural Brain Abnormalities Caused by Compound Heterozygous Mutations in ATP1A3

by August A. Allocco, Sheng Chih Jin, Sheng Chih Jin, Phan Q. Duy, Charuta G. Furey, Xue Zeng, Xue Zeng, Weilai Dong, Carol Nelson-Williams, Jason K. Karimy, Tyrone DeSpenza, Le T. Hao, Benjamin Reeves, Shozeb Haider, Murat Gunel, Murat Gunel, Richard P. Lifton, Richard P. Lifton, Kristopher T. Kahle, Kristopher T. Kahle, Kristopher T. Kahle, Kristopher T. Kahle
Published 2019-09-01

Trends in peptic ulcer disease and the identification of Helicobacter Pylori as a causative organism: Population-based estimates from the US nationwide inpatient sample

by Bronislava Bashinskaya, Brian V Nahed, Navid Redjal, Kristopher T Kahle, Brian P Walcott
Published 2011-01-01

Regulated phosphorylation of the K-Cl cotransporter KCC3 at dual C-terminal threonines is a potent switch of intracellular potassium content and cell volume homeostasis

by Norma C. Adragna, Nagendra Babu Ravilla, Peter K. Lauf, Peter K. Lauf, Gulnaz eBegum, Arjun R. Khanna, Dandan eSun, Dandan eSun, Kristopher T Kahle, Kristopher T Kahle
Published 2015-07-01

Malignant Cerebellar Edema Subsequent to Accidental Prescription Opioid Intoxication in Children

by Daniel Duran, Robert D. Messina, Lauren A. Beslow, Lauren A. Beslow, Julio D. Montejo, Julio D. Montejo, Jason K. Karimy, Charuta Gavankar Furey, Charuta Gavankar Furey, Alison D. Sheridan, Gordon Sze, Yanki Yarman, Michael L. DiLuna, Michael L. DiLuna, Kristopher T. Kahle, Kristopher T. Kahle, Kristopher T. Kahle
Published 2017-07-01

Interfacility helicopter ambulance transport of neurosurgical patients: observations, utilization, and outcomes from a quaternary level care hospital.

by Brian P Walcott, Jean-Valery Coumans, Matthew K Mian, Brian V Nahed, Kristopher T Kahle
Published 2011-01-01

Analysis workflow to assess de novo genetic variants from human whole-exome sequencing

by Nicholas S. Diab, Spencer King, Weilai Dong, Garrett Allington, Amar Sheth, Samuel T. Peters, Kristopher T. Kahle, Sheng Chih Jin
Published 2021-03-01

Current view on the functional regulation of the neuronal K+-Cl- cotransporter KCC2

by Igor eMedina, Igor eMedina, Perrine eFriedel, Perrine eFriedel, Claudio eRivera, Claudio eRivera, Claudio eRivera, Kristopher T Kahle, Kristopher T Kahle, Nazim eKourdougli, Nazim eKourdougli, Pavel eUvarov, Christophe ePellegrino, Christophe ePellegrino
Published 2014-02-01

Molecular Genetics and Complex Inheritance of Congenital Heart Disease

by Nicholas S. Diab, Syndi Barish, Weilai Dong, Shujuan Zhao, Garrett Allington, Xiaobing Yu, Kristopher T. Kahle, Martina Brueckner, Sheng Chih Jin
Published 2021-06-01

Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma

by Elena I. Fomchenko, Benjamin C. Reeves, William Sullivan, Asher M. Marks, Anita Huttner, Kristopher T. Kahle, E. Zeynep Erson‐Omay
Published 2021-02-01

Glioblastoma mimicking an arteriovenous malformation

by Arjun eKhanna, Andrew S Venteicher, Brian Patrick Walcott, Kristopher T Kahle, Daniel A Mordes, Christopher M William, Zoher eGhogawala, Christopher S Ogilvy
Published 2013-09-01

Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia

by Nancy D Merner, Madison R Chandler, Cynthia eBourassa, Bo eLiang, Arjun R Khanna, Patrick eDion, Guy eRouleau, Kristopher eKahle
Published 2015-10-01

Craniectomy for malignant cerebral infarction: prevalence and outcomes in US hospitals.

by Brian P Walcott, Elena V Kuklina, Brian V Nahed, Mary G George, Kristopher T Kahle, J Marc Simard, Wael F Asaad, Jean-Valery C E Coumans
Published 2011-01-01

SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus

by Sheng Chih Jin, Charuta G. Furey, Xue Zeng, August Allocco, Carol Nelson‐Williams, Weilai Dong, Jason K. Karimy, Kevin Wang, Shaojie Ma, Eric Delpire, Kristopher T. Kahle
Published 2019-09-01

GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl−-sensitive WNK1 kinase

by Martin Heubl, Jinwei Zhang, Jessica C. Pressey, Sana Al Awabdh, Marianne Renner, Ferran Gomez-Castro, Imane Moutkine, Emmanuel Eugène, Marion Russeau, Kristopher T. Kahle, Jean Christophe Poncer, Sabine Lévi
Published 2017-11-01

Correction: Bumetanide Enhances Phenobarbital Efficacy in a Rat Model of Hypoxic Neonatal Seizures

by Ryan T. Cleary, Hongyu Sun, Thanhthao Huynh, Simon M. Manning, Yijun Li, Alexander Rotenberg, Delia M. Talos, Kristopher T. Kahle, Michele Jackson, Sanjay N. Rakhade, Gerard T. Berry, Frances E. Jensen
Published 2013-01-01

Correction: Bumetanide Enhances Phenobarbital Efficacy in a Rat Model of Hypoxic Neonatal Seizures.

by Ryan T. Cleary, Hongyu Sun, Thanhthao Huynh, Simon M. Manning, Yijun Li, Alexander Rotenberg, Delia M. Talos, Kristopher T. Kahle, Michele Jackson, Sanjay N. Rakhade, Gerard T. Berry, Frances E. Jensen
Published 2013-01-01

Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.

by Ryan T Cleary, Hongyu Sun, Thanhthao Huynh, Simon M Manning, Yijun Li, Alexander Rotenberg, Delia M Talos, Kristopher T Kahle, Michele Jackson, Sanjay N Rakhade, Gerard T Berry, Frances E Jensen
Published 2013-01-01

Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a

by Jinwei Zhang, Mohammad Iqbal H. Bhuiyan, Ting Zhang, Jason K. Karimy, Zhijuan Wu, Victoria M. Fiesler, Jingfang Zhang, Huachen Huang, Md Nabiul Hasan, Anna E. Skrzypiec, Mariusz Mucha, Daniel Duran, Wei Huang, Robert Pawlak, Lesley M. Foley, T. Kevin Hitchens, Margaret B. Minnigh, Samuel M. Poloyac, Seth L. Alper, Bradley J. Molyneaux, Andrew J. Trevelyan, Kristopher T. Kahle, Dandan Sun, Xianming Deng
Published 2020-01-01