Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA

by Krystal K. Lum, Timothy R. Howard, Catherina Pan, Ileana M. Cristea
Published 2019-07-01

Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infe...

by Benjamin A. Diner, Krystal K. Lum, Jared E. Toettcher, Ileana M. Cristea
Published 2016-11-01

The DNA Sensor IFIX Drives Proteome Alterations To Mobilize Nuclear and Cytoplasmic Antiviral Responses, with Its Acetylation Acting as a Localization Toggle

by Timothy R. Howard, Marni S. Crow, Todd M. Greco, Krystal K. Lum, Tuo Li, Ileana M. Cristea
Published 2021-06-01

Adenovirus Remodeling of the Host Proteome and Host Factors Associated with Viral Genomes

by Joseph M. Dybas, Krystal K. Lum, Katarzyna Kulej, Emigdio D. Reyes, Richard Lauman, Matthew Charman, Caitlin E. Purman, Robert T. Steinbock, Nicholas Grams, Alexander M. Price, Lydia Mendoza, Benjamin A. Garcia, Matthew D. Weitzman
Published 2021-03-01