Tau Pathology and Adult Hippocampal Neurogenesis: What Tau Mouse Models Tell us?

by Sarah Houben, Mégane Homa, Zehra Yilmaz, Karelle Leroy, Jean-Pierre Brion, Kunie Ando
Published 2021-02-01

Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model

by Sarah Houben, Karelle Leroy, Kunie Ando, Zehra Yilmaz, Cyprien Widomski, Luc Buée, Jean-Pierre Brion
Published 2019-07-01

Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease

by Kunie Ando, Christophe Erneux, Mégane Homa, Sarah Houben, Marie-Ange de Fisenne, Jean-Pierre Brion, Karelle Leroy
Published 2021-02-01

Two-dimensional electrophoresis of tau mutants reveals specific phosphorylation pattern likely linked to early tau conformational changes.

by Alexis Bretteville, Kunie Ando, Antoine Ghestem, Anne Loyens, Séverine Bégard, Jean-Claude Beauvillain, Nicolas Sergeant, Malika Hamdane, Luc Buée
Published 2009-01-01

Alzheimer's Disease: Tau Pathology and Dysfunction of Endocytosis

by Kunie Ando, Sarah Houben, Mégane Homa, Marie-Ange de Fisenne, Marie-Claude Potier, Christophe Erneux, Jean-Pierre Brion, Karelle Leroy
Published 2021-01-01

Intravenous Injection of PHF-Tau Proteins From Alzheimer Brain Exacerbates Neuroinflammation, Amyloid Beta, and Tau Pathologies in 5XFAD Transgenic Mice

by Sarah Houben, Marie-Ange de Fisenne, Kunie Ando, Virginie Vanden Dries, Luc Poncelet, Zehra Yilmaz, Salwa Mansour, Robert De Decker, Jean-Pierre Brion, Karelle Leroy
Published 2020-07-01

Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice

by Céline Héraud, Doris Goufak, Kunie Ando, Karelle Leroy, Valérie Suain, Zehra Yilmaz, Robert De Decker, Michèle Authelet, Vincent Laporte, Jean-Noël Octave, Jean-Pierre Brion
Published 2014-02-01

Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in A...

by Kunie Ando, Karen Tomimura, Véronique Sazdovitch, Valérie Suain, Zehra Yilmaz, Michèle Authelet, Marième Ndjim, Cristina Vergara, Mounir Belkouch, Marie-Claude Potier, Charles Duyckaerts, Jean-Pierre Brion
Published 2016-10-01

de novo MAPT mutation G335A causes severe brain atrophy, 3R and 4R PHF-tau pathology and early onset frontotemporal dementia

by Kunie Ando, Lorenzo Ferlini, Valérie Suain, Zehra Yilmaz, Salwa Mansour, Isabelle Le Ber, Cécile Bouchard, Karelle Leroy, Alexandra Durr, Fabienne Clot, Marie Sarazin, Jean-Christophe Bier, Jean-Pierre Brion
Published 2020-06-01

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

by Anna Doshina, Florian Gourgue, Michiho Onizuka, Remi Opsomer, Peng Wang, Kunie Ando, Bernadette Tasiaux, Ilse Dewachter, Pascal Kienlen-Campard, Jean-Pierre Brion, Philippe Gailly, Jean-Noël Octave, Nathalie Pierrot
Published 2017-03-01

The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease

by Kunie Ando, Marième Ndjim, Sabrina Turbant, Gaëlle Fontaine, Gustavo Pregoni, Luce Dauphinot, Zehra Yilmaz, Valérie Suain, Salwa Mansour, Michèle Authelet, Robert De Dekker, Karelle Leroy, Benoît Delatour, Brain Bank NeuroCEB Neuropathology Network, Charles Duyckaerts, Marie-Claude Potier, Jean-Pierre Brion
Published 2020-06-01