Investigation of Hot Spot Region in XIAP Inhibitor Binding Site by Fragment Molecular Orbital Method

by Hocheol Lim, Xuemei Jin, Jongwan Kim, Sungbo Hwang, Ki Beom Shin, Jiwon Choi, Ky-Youb Nam, Kyoung Tai No
Published 2019-01-01

Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor

by Hwani Ryu, Ky-Youb Nam, Hyo Jeong Kim, Jie-Young Song, Sang-Gu Hwang, Jae Sung Kim, Joon Kim, Jiyeon Ahn
Published 2021-07-01

Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1.

by Ganipisetti Srinivasrao, Jung-Eun Park, Sungmin Kim, Mija Ahn, Chaejoon Cheong, Ky-Youb Nam, Pethaiah Gunasekaran, Eunha Hwang, Nam-Hyung Kim, Song Yub Shin, Kyung S Lee, Eunkyung Ryu, Jeong Kyu Bang
Published 2014-01-01

Modulation of intracellular calcium levels by calcium lactate affects colon cancer cell motility through calcium-dependent calpain.

by Pasupathi Sundaramoorthy, Jae Jun Sim, Yeong-Su Jang, Siddhartha Kumar Mishra, Keun-Yeong Jeong, Poonam Mander, Oh Byung Chul, Won-Sik Shim, Seung Hyun Oh, Ky-Youb Nam, Hwan Mook Kim
Published 2015-01-01

De novo design and synthesis of ultra-short peptidomimetic antibiotics having dual antimicrobial and anti-inflammatory activities.

by Ravichandran N Murugan, Binu Jacob, Mija Ahn, Eunha Hwang, Hoik Sohn, Hyo-Nam Park, Eunjung Lee, Ji-Hyung Seo, Chaejoon Cheong, Ky-Youb Nam, Jae-Kyung Hyun, Ki-Woong Jeong, Yangmee Kim, Song Yub Shin, Jeong Kyu Bang
Published 2013-01-01