Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder

by Giuseppe Galvani, Nicola Mottolese, Laura Gennaccaro, Manuela Loi, Giorgio Medici, Marianna Tassinari, Claudia Fuchs, Elisabetta Ciani, Stefania Trazzi
Published 2021-07-01

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder

by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani
Published 2018-01-01

Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of <i>CDKL5</i> Deficiency Disorder

by Manuela Loi, Laura Gennaccaro, Claudia Fuchs, Stefania Trazzi, Giorgio Medici, Giuseppe Galvani, Nicola Mottolese, Marianna Tassinari, Roberto Rimondini Giorgini, Andrea Milelli, Elisabetta Ciani
Published 2021-05-01

Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist

by Elisa Ren, Vincenzo Roncacé, Stefania Trazzi, Claudia Fuchs, Giorgio Medici, Laura Gennaccaro, Manuela Loi, Giuseppe Galvani, Keqiang Ye, Roberto Rimondini, Giorgio Aicardi, Giorgio Aicardi, Elisabetta Ciani
Published 2019-04-01

A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder

by Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali, Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
Published 2021-06-01

Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

by Stefano Rossi, Monia Savi, Marta Mazzola, Silvana Pinelli, Rossella Alinovi, Laura Gennaccaro, Alessandra Pagliaro, Viviana Meraviglia, Maricla Galetti, Omar Lozano-Garcia, Alessandra Rossini, Caterina Frati, Angela Falco, Federico Quaini, Leonardo Bocchi, Donatella Stilli, Stéphane Lucas, Matteo Goldoni, Emilio Macchi, Antonio Mutti, Michele Miragoli
Published 2019-06-01