Steering CAR T cells to distinguish friend from foe

by Hillary G. Caruso, Amy B. Heimberger, Laurence J. N. Cooper
Published 2019-10-01

Peripheral and Thymic Foxp3+ Regulatory T Cells in Search of Origin, Distinction and Function

by Chetan eDhamne, Yeonseok eChung, Amin Majid Alousi, Laurence J.N. Cooper, Dat Quoc Tran
Published 2013-08-01

Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials.

by Bipulendu Jena, Sourindra Maiti, Helen Huls, Harjeet Singh, Dean A Lee, Richard E Champlin, Laurence J N Cooper
Published 2013-01-01

Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering.

by Shan Zong, Tiejuan Mi, Leo G Flores, Amir Alpert, Simon Olivares, Krina Patel, Sourindra Maiti, George Mcnamara, Laurence J N Cooper, Hiroki Torikai
Published 2020-01-01

Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors.

by Radhika Thokala, Simon Olivares, Tiejuan Mi, Sourindra Maiti, Drew Deniger, Helen Huls, Hiroki Torikai, Harjeet Singh, Richard E Champlin, Tamara Laskowski, George McNamara, Laurence J N Cooper
Published 2016-01-01

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

by Niannian Ji, Neelam Mukherjee, Edwin E. Morales, Maggie E. Tomasini, Vincent Hurez, Tyler J. Curiel, Getahun Abate, Dan F. Hoft, Xiang-Ru Zhao, Jon Gelfond, Sourindra Maiti, Laurence J.N. Cooper, Robert S. Svatek
Published 2019-08-01

Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells.

by Harjeet Singh, Matthew J Figliola, Margaret J Dawson, Simon Olivares, Ling Zhang, Ge Yang, Sourindra Maiti, Pallavi Manuri, Vladimir Senyukov, Bipulendu Jena, Partow Kebriaei, Richard E Champlin, Helen Huls, Laurence J N Cooper
Published 2013-01-01

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells.

by Cecele J Denman, Vladimir V Senyukov, Srinivas S Somanchi, Prasad V Phatarpekar, Lisa M Kopp, Jennifer L Johnson, Harjeet Singh, Lenka Hurton, Sourindra N Maiti, M Helen Huls, Richard E Champlin, Laurence J N Cooper, Dean A Lee
Published 2012-01-01

Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations.

by Drew C Deniger, Jianqiang Yu, M Helen Huls, Matthew J Figliola, Tiejuan Mi, Sourindra N Maiti, George F Widhopf, Lenka V Hurton, Radhika Thokala, Harjeet Singh, Simon Olivares, Richard E Champlin, William G Wierda, Thomas J Kipps, Laurence J N Cooper
Published 2015-01-01

Repetitive Noninvasive Monitoring of HSV1-tk-Expressing T Cells Intravenously Infused into Nonhuman Primates Using Positron Emission Tomography and Computed Tomography with F-FEAU

by Gianpietro Dotti, Mei Tian, Barbara Savoldo, Amer Najjar, Laurence J.N. Cooper, James Jackson, Amanda Smith, Osama Mawlawi, Rajesh Uthamanthil, Agatha Borne, David Brammer, Vincenzo Paolillo, Mian Alauddin, Carlos Gonzalez, David Steiner, William K. Decker, Frank Marini, Steven Kornblau, Catherine M. Bollard, Elizabeth J. Shpall, Juri G. Gelovani
Published 2009-07-01

Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.

by Nina Shah, Beatriz Martin-Antonio, Hong Yang, Stephanie Ku, Dean A Lee, Laurence J N Cooper, William K Decker, Sufang Li, Simon N Robinson, Takuya Sekine, Simrit Parmar, John Gribben, Michael Wang, Katy Rezvani, Eric Yvon, Amer Najjar, Jared Burks, Indreshpal Kaur, Richard E Champlin, Catherine M Bollard, Elizabeth J Shpall
Published 2013-01-01

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

by Lingegowda S. Mangala, Hongyu Wang, Dahai Jiang, Sherry Y. Wu, Anoma Somasunderam, David E. Volk, Ganesh L. R. Lokesh, Xin Li, Sunila Pradeep, Xianbin Yang, Monika Haemmerle, Cristian Rodriguez-Aguayo, Archana S Nagaraja, Rajesha Rupaimoole, Emine Bayraktar, Recep Bayraktar, Li Li, Takemi Tanaka, Wei Hu, Cristina Ivan, Kshipra M Gharpure, Michael H. McGuire, Varatharasa Thiviyanathan, Xinna Zhang, Sourindra N. Maiti, Nataliya Bulayeva, Hyun-Jin Choi, Piotr L. Dorniak, Laurence J.N. Cooper, Kevin P. Rosenblatt, Gabriel Lopez-Berestein, David G. Gorenstein, Anil K. Sood
Published 2021-04-01

A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer

by Sherry Y. Wu, Rajesha Rupaimoole, Fangrong Shen, Sunila Pradeep, Chad V. Pecot, Cristina Ivan, Archana S. Nagaraja, Kshipra M. Gharpure, Elizabeth Pham, Hiroto Hatakeyama, Michael H. McGuire, Monika Haemmerle, Viviana Vidal-Anaya, Courtney Olsen, Cristian Rodriguez-Aguayo, Justyna Filant, Ehsan A. Ehsanipour, Shelley M. Herbrich, Sourindra N. Maiti, Li Huang, Ji Hoon Kim, Xinna Zhang, Hee-Dong Han, Guillermo N. Armaiz-Pena, Elena G. Seviour, Sue Tucker, Min Zhang, Da Yang, Laurence J. N. Cooper, Rouba Ali-Fehmi, Menashe Bar-Eli, Ju-Seog Lee, Prahlad T. Ram, Keith A. Baggerly, Gabriel Lopez-Berestein, Mien-Chie Hung, Anil K. Sood
Published 2016-04-01