Fracture healing of the mandible is impaired in a Fgfr3N534K/+ mouse model of hypochondroplasia

by Anne Morice, Loisay Lea, Laurence Legeai Mallet
Published 2021-04-01

Fgfr3 gain-of-function mutation impacts bone homeostasis in hypochondroplasia mouse model

by Léa Loisay, Davide Komla Ebri, Nabil Kaci, J.H. Duncan Bassett, Graham R. Williams, Laurence Legeai Mallet
Published 2020-10-01

Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dwarfism

by Brandon M. Wagner, Jerid W. Robinson, Yun-Wen Lin, Yi-Ching Lee, Nabil Kaci, Laurence Legeai-Mallet, Lincoln R. Potter
Published 2021-05-01

New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profiling.

by Laurent Schibler, Linda Gibbs, Catherine Benoist-Lasselin, Charles Decraene, Jelena Martinovic, Philippe Loget, Anne-Lise Delezoide, Marie Gonzales, Arnold Munnich, Jean-Philippe Jais, Laurence Legeai-Mallet
Published 2009-01-01

The impact of polyphenols on chondrocyte growth and survival: a preliminary report

by Salvador Fernández-Arroyo, Fernando Huete-Toral, María Jesús Pérez de Lara, María de la Luz Cádiz-Gurrea, Laurence Legeai-Mallet, Vicente Micol, Antonio Segura-Carretero, Jorge Joven, Jesús Pintor
Published 2015-10-01

The impairment of MAGMAS function in human is responsible for a severe skeletal dysplasia.

by Cybel Mehawej, Agnès Delahodde, Laurence Legeai-Mallet, Valérie Delague, Nabil Kaci, Jean-Pierre Desvignes, Zoha Kibar, José-Mario Capo-Chichi, Eliane Chouery, Arnold Munnich, Valérie Cormier-Daire, André Mégarbané
Published 2014-05-01

Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth

by Leia C. Shuhaibar, Nabil Kaci, Jeremy R. Egbert, Thibault Horville, Léa Loisay, Giulia Vigone, Tracy F. Uliasz, Emilie Dambroise, Mark R. Swingle, Richard E. Honkanen, Martin Biosse Duplan, Laurinda A. Jaffe, Laurence Legeai-Mallet
Published 2021-05-01