The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structures.

by Ashwini Kamath-Loeb, Lawrence A Loeb, Michael Fry
Published 2012-01-01

Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage.

by Scott R Kennedy, Jesse J Salk, Michael W Schmitt, Lawrence A Loeb
Published 2013-01-01

Detection of Ultra-Rare Mitochondrial Mutations in Breast Stem Cells by Duplex Sequencing.

by Eun Hyun Ahn, Kensen Hirohata, Brendan F Kohrn, Edward J Fox, Chia-Cheng Chang, Lawrence A Loeb
Published 2015-01-01

Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461.

by James I Mullins, Laura Heath, James P Hughes, Jessica Kicha, Sheila Styrchak, Kim G Wong, Ushnal Rao, Alexis Hansen, Kevin S Harris, Jean-Pierre Laurent, Deyu Li, Jeffrey H Simpson, John M Essigmann, Lawrence A Loeb, Jeffrey Parkins
Published 2011-01-01

Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

by Jesse J. Salk, Kaitlyn Loubet-Senear, Elisabeth Maritschnegg, Charles C. Valentine, Lindsey N. Williams, Jacob E. Higgins, Reinhard Horvat, Adriaan Vanderstichele, Daniela Nachmanson, Kathryn T. Baker, Mary J. Emond, Emily Loter, Maria Tretiakova, Thierry Soussi, Lawrence A. Loeb, Robert Zeillinger, Paul Speiser, Rosa Ana Risques
Published 2019-07-01