Editorial: “Humanized” Large Animal Cancer Models: Accelerating Time and Effectiveness of Clinical Trials

by Kyle M. Schachtschneider, Gregers Jungersen, Lawrence B. Schook, Lawrence B. Schook, Dhanansayan Shanmuganayagam
Published 2019-08-01

Translating Human Cancer Sequences Into Personalized Porcine Cancer Models

by Chunlong Xu, Sen Wu, Lawrence B. Schook, Lawrence B. Schook, Lawrence B. Schook, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Kyle M. Schachtschneider
Published 2019-02-01

Editorial: Building Strategies for Porcine Cancer Models

by Tiago Collares, Fabiana K. Seixas, Laurie A. Rund, Lawrence B. Schook, Lawrence B. Schook
Published 2018-10-01

Transcriptional Profiling of Porcine HCC Xenografts Provides Insights Into Tumor Cell Microenvironment Signaling

by Shovik S. Patel, Amitha Sandur, Mohammed El-Kebir, Ron C. Gaba, Lawrence B. Schook, Lawrence B. Schook, Lawrence B. Schook, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Kyle M. Schachtschneider
Published 2021-04-01

The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery

by Natalia V. Segatto, Mariana H. Remião, Kyle M. Schachtschneider, Fabiana K. Seixas, Lawrence B. Schook, Lawrence B. Schook, Tiago Collares
Published 2017-12-01

Emerging technologies to create inducible and genetically defined porcine cancer models

by Lawrence B Schook, Lawrence B Schook, Laurie A. Rund, Karine eBegnini, Mariana Härter Remião, Fabiana Kommling Seixas, Tiago V. Collares
Published 2016-02-01

Genetic Resources, Genome Mapping and Evolutionary Genomics of the Pig (Sus scrofa)

by Kefei Chen, Tara Baxter, William M. Muir, Martien A. Groenen, Lawrence B. Schook
Published 2007-01-01

Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Respon...

by Nana H. Overgaard, Nana H. Overgaard, Daniel R. Principe, Kyle M. Schachtschneider, Jeanne Toft Jakobsen, Laurie A. Rund, Paul J. Grippo, Lawrence B. Schook, Lawrence B. Schook, Gregers Jungersen
Published 2018-06-01

Age and diet affect gene expression profile in canine skeletal muscle.

by Ingmar S Middelbos, Brittany M Vester, Lisa K Karr-Lilienthal, Lawrence B Schook, Kelly S Swanson
Published 2009-01-01

Gene expression profiles of colonic mucosa in healthy young adult and senior dogs.

by Dong Yong Kil, Brittany M Vester Boler, Carolyn J Apanavicius, Lawrence B Schook, Kelly S Swanson
Published 2010-01-01

Age and diet affect gene expression profiles in canine liver tissue.

by Dong Yong Kil, Brittany M Vester Boler, Carolyn J Apanavicius, Lawrence B Schook, Kelly S Swanson
Published 2010-01-01

Modulation of systemic immune responses through commensal gastrointestinal microbiota.

by Kyle M Schachtschneider, Carl J Yeoman, Richard E Isaacson, Bryan A White, Lawrence B Schook, Maria Pieters
Published 2013-01-01

Adaptive Evolution of Toll-Like Receptors (TLRs) in the Family Suidae.

by Kwame A Darfour-Oduro, Hendrik-Jan Megens, Alfred L Roca, Martien A M Groenen, Lawrence B Schook
Published 2015-01-01

Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes.

by Radhika S Ganu, Yasuko Ishida, Markos Koutmos, Sergios-Orestis Kolokotronis, Alfred L Roca, Timothy A Garrow, Lawrence B Schook
Published 2015-01-01

Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas

by Kyle M. Schachtschneider, Yingkai Liu, Suvi Mäkeläinen, Ole Madsen, Laurie A. Rund, Martien A. M. Groenen, Lawrence B. Schook
Published 2017-06-01

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

by Kyle M. Schachtschneider, Regina M. Schwind, Jordan Newson, Nickolas Kinachtchouk, Mark Rizko, Nasya Mendoza-Elias, Paul Grippo, Daniel R. Principe, Alex Park, Nana H. Overgaard, Gregers Jungersen, Kelly D. Garcia, Ajay V. Maker, Laurie A. Rund, Howard Ozer, Ron C. Gaba, Lawrence B. Schook, Lawrence B. Schook
Published 2017-08-01

TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth.

by Megha Singhal, Mahsa Khatibeghdami, Daniel R Principe, Georgina E Mancinelli, Kyle M Schachtschneider, Lawrence B Schook, Paul J Grippo, Sam R Grimaldo
Published 2019-01-01

Regions of homozygosity in the porcine genome: consequence of demography and the recombination landscape.

by Mirte Bosse, Hendrik-Jan Megens, Ole Madsen, Yogesh Paudel, Laurent A F Frantz, Lawrence B Schook, Richard P M A Crooijmans, Martien A M Groenen
Published 2012-01-01

Genome-wide footprints of pig domestication and selection revealed through massive parallel sequencing of pooled DNA.

by Andreia J Amaral, Luca Ferretti, Hendrik-Jan Megens, Richard P M A Crooijmans, Haisheng Nie, Sebastian E Ramos-Onsins, Miguel Perez-Enciso, Lawrence B Schook, Martien A M Groenen
Published 2011-04-01

Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults

by Kyle M. Schachtschneider, Michael E. Welge, Loretta S. Auvil, Sulalita Chaki, Laurie A. Rund, Ole Madsen, Monica R.P. Elmore, Rodney W. Johnson, Martien A.M. Groenen, Lawrence B. Schook
Published 2020-02-01