Hsp90 orchestrates stress response signaling governing fungal drug resistance.

by Leah E Cowen
Published 2009-08-01

Surviving the heat of the moment: a fungal pathogens perspective.

by Michelle D Leach, Leah E Cowen
Published 2013-03-01

The Rise of Fungi: A Report on the CIFAR Program Fungal Kingdom: Threats & Opportunities Inaugural Meeting

by Nicola T. Case, Joseph Heitman, Leah E. Cowen
Published 2020-06-01

Insights into the host-pathogen interaction: C. albicans manipulation of macrophage pyroptosis

by Teresa R. O’Meara, Leah E. Cowen
Published 2018-11-01

Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States.

by Stephanie Diezmann, Michelle D Leach, Leah E Cowen
Published 2015-01-01

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

by Nicole Robbins, Michelle D. Leach, Leah E. Cowen
Published 2012-10-01

Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis

by Saif Hossain, Emma Lash, Amanda O. Veri, Leah E. Cowen
Published 2021-02-01

Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations

by Jessica A. Hill, Teresa R. O’Meara, Leah E. Cowen
Published 2015-02-01

Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations.

by Jessica A Hill, Ron Ammar, Dax Torti, Corey Nislow, Leah E Cowen
Published 2013-04-01

Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry.

by Stephanie Diezmann, Magali Michaut, Rebecca S Shapiro, Gary D Bader, Leah E Cowen
Published 2012-01-01

Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance.

by Anna M Selmecki, Keely Dulmage, Leah E Cowen, James B Anderson, Judith Berman
Published 2009-10-01

Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation.

by Jason A Lee, Nicole Robbins, Jinglin L Xie, Troy Ketela, Leah E Cowen
Published 2016-11-01

The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance.

by Rebecca S Shapiro, Aimee K Zaas, Marisol Betancourt-Quiroz, John R Perfect, Leah E Cowen
Published 2012-01-01

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast.

by Michelle D Leach, Susan Budge, Louise Walker, Carol Munro, Leah E Cowen, Alistair J P Brown
Published 2012-12-01

Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes

by Michelle E Maxson, Xenia Naj, Teresa R O'Meara, Jonathan D Plumb, Leah E Cowen, Sergio Grinstein
Published 2018-03-01

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.

by Sheena D Singh, Nicole Robbins, Aimee K Zaas, Wiley A Schell, John R Perfect, Leah E Cowen
Published 2009-07-01

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris

by Kali R. Iyer, Luke Whitesell, John A. Porco, Thomas Henkel, Lauren E. Brown, Nicole Robbins, Leah E. Cowen
Published 2020-03-01

Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A

by Jinglin L. Xie, Teresa R. O’Meara, Elizabeth J. Polvi, Nicole Robbins, Leah E. Cowen, Aaron P. Mitchell
Published 2017-03-01

Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans

by Tavia Caplan, Elizabeth J. Polvi, Jinglin L. Xie, Shoshana Buckhalter, Michelle D. Leach, Nicole Robbins, Leah E. Cowen
Published 2018-05-01

Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic Candida Species

by Nicole M. Revie, Nicole Robbins, Luke Whitesell, John R. Frost, Solomon D. Appavoo, Andrei K. Yudin, Leah E. Cowen
Published 2020-04-01