Structure-function analysis of the Anopheles gambiae LRIM1/APL1C complex and its interaction with complement C3-like protein TEP1.

by Michael Povelones, Leanna M Upton, Katarzyna A Sala, George K Christophides
Published 2011-04-01

The CLIP-domain serine protease homolog SPCLIP1 regulates complement recruitment to microbial surfaces in the malaria mosquito Anopheles gambiae.

by Michael Povelones, Lavanya Bhagavatula, Hassan Yassine, Lee Aun Tan, Leanna M Upton, Mike A Osta, George K Christophides
Published 2013-01-01

A novel model fitted to multiple life stages of malaria for assessing efficacy of transmission-blocking interventions

by Ellie Sherrard-Smith, Thomas S. Churcher, Leanna M. Upton, Katarzyna A. Sala, Sara E. Zakutansky, Hannah C. Slater, Andrew M. Blagborough, Michael Betancourt
Published 2017-04-01

Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

by Ellie Sherrard-Smith, Katarzyna A Sala, Michael Betancourt, Leanna M Upton, Fiona Angrisano, Merribeth J Morin, Azra C Ghani, Thomas S Churcher, Andrew M Blagborough
Published 2018-06-01

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts.

by Thomas S Churcher, Robert E Sinden, Nick J Edwards, Ian D Poulton, Thomas W Rampling, Patrick M Brock, Jamie T Griffin, Leanna M Upton, Sara E Zakutansky, Katarzyna A Sala, Fiona Angrisano, Adrian V S Hill, Andrew M Blagborough
Published 2017-01-01