Two-step generation of mesenchymal stem/stromal cells from human pluripotent stem cells with reinforced efficacy upon osteoarthritis rabbits by HA hydrogel

by Leisheng Zhang, Yimeng Wei, Ying Chi, Dengke Liu, Sijun Yang, Zhongchao Han, Zongjin Li
Published 2021-01-01

Human Supernumerary Teeth-Derived Apical Papillary Stem Cells Possess Preferable Characteristics and Efficacy on Hepatic Fibrosis in Mice

by Jun Yao, Nan Chen, Xiaojing Wang, Leisheng Zhang, Jiali Huo, Ying Chi, Zongjin Li, Zhongchao Han
Published 2020-01-01

Multifaceted Optimization of MSC-Based Formulation upon Sodium Iodoacetate-Induced Osteoarthritis Models by Combining Advantageous HA/PG Hydrogel and Fluorescent Tracer

by Ai-tong Wang, Meng Zhao, Ying Feng, Honghong Jia, Leisheng Zhang, Hao Yu, Zongjin Li, Zhibo Han, Zhongchao Han
Published 2021-01-01

Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor d-1-methyl-tryptophan

by Xiaolong Zhang, Yuanyuan Yang, Leisheng Zhang, Yang Lu, Qing Zhang, Dongmei Fan, Yizhi Zhang, Yanjun Zhang, Zhou Ye, Dongsheng Xiong
Published 2017-02-01

Bone marrow-derived mesenchymal stem/stromal cells in patients with acute myeloid leukemia reveal transcriptome alterations and deficiency in cellular vitality

by Leisheng Zhang, Ying Chi, Yimeng Wei, Wenxia Zhang, Fuxu Wang, Lei Zhang, Linglin Zou, Baoquan Song, Xing Zhao, Zhongchao Han
Published 2021-06-01

MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME

by Leisheng Zhang, Hongtao Wang, Cuicui Liu, Qingqing Wu, Pei Su, Dan Wu, Jiaojiao Guo, Wen Zhou, Yuanfu Xu, Lihong Shi, Jiaxi Zhou
Published 2018-08-01

Thrombopoietin knock-in augments platelet generation from human embryonic stem cells

by Leisheng Zhang, Cuicui Liu, Hongtao Wang, Dan Wu, Pei Su, Mengge Wang, Jiaojiao Guo, Shixuan Zhao, Shuxu Dong, Wen Zhou, Cameron Arakaki, Xiaobing Zhang, Jiaxi Zhou
Published 2018-07-01

Multifaceted characterization of the signatures and efficacy of mesenchymal stem/stromal cells in acquired aplastic anemia

by Jiali Huo, Leisheng Zhang, Xiang Ren, Chengwen Li, Xingxin Li, Peiyuan Dong, Xuan Zheng, Jinbo Huang, Yingqi Shao, Meili Ge, Jing Zhang, Min Wang, Neng Nie, Peng Jin, Yizhou Zheng
Published 2020-02-01

JNKi- and DAC-programmed mesenchymal stem/stromal cells from hESCs facilitate hematopoiesis and alleviate hind limb ischemia

by Yimeng Wei, Huixing Hou, Leisheng Zhang, Nianhuan Zhao, Chengwen Li, Jiali Huo, Ying Liu, Wenxia Zhang, Zongjin Li, Dengke Liu, Zhibo Han, Lei Zhang, Baoquan Song, Ying Chi, Zhongchao Han
Published 2019-06-01

Systematic comparison of hUC-MSCs at various passages reveals the variations of signatures and therapeutic effect on acute graft-versus-host disease

by Qinjun Zhao, Leisheng Zhang, Yimeng Wei, Hao Yu, Linglin Zou, Jiali Huo, Hongju Yang, Baoquan Song, Teng Wei, Dan Wu, Wenxia Zhang, Lei Zhang, Dengke Liu, Zongjin Li, Ying Chi, Zhibo Han, Zhongchao Han
Published 2019-11-01