Carbon monoxide-releasing molecules
Carbon monoxide-releasing molecules (CORMs) are chemical compounds designed to release controlled amounts of carbon monoxide (CO). CORMs are being developed as potential therapeutic agents to locally deliver CO to cells and tissues, thus overcoming limitations of CO gas inhalation protocols.CO is best known for its toxicity in carbon monoxide poisoning at high doses. However, CO is a gasotransmitter and supplemental low dosage of CO has been linked to therapeutic benefits. Pre-clinical research has focused on CO's anti-inflammatory activity with significant applications in cardiovascular disease, oncology, transplant surgery, and neuroprotection. Provided by Wikipedia
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1by Barbara Wegiel, Thomas Jiborn, Magnus Abrahamson, Leszek Helczynski, Leo Otterbein, Jenny Liao Persson, Jenny Liao Persson, Anders BjartellGet full text
Published 2009-11-01
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