Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease

by Vishnu Hosur, Bonnie L. Lyons, Lisa M. Burzenski, Leonard D. Shultz
Published 2017-11-01

Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis

by Vishnu Hosur, Benjamin E. Low, Leonard D. Shultz, Michael V. Wiles
Published 2017-08-01

Loss of function of the mouse Sharpin gene results in Peyer's patch regression.

by Rosemarie Seymour, Bobbi-Jo Shirley, Harm Hogenesch, Leonard D Shultz, John P Sundberg
Published 2013-01-01

Role of MicroRNA in Inflammatory Bowel Disease: Clinical Evidence and the Development of Preclinical Animal Models

by Kanika Suri, Jason A. Bubier, Michael V. Wiles, Leonard D. Shultz, Mansoor M. Amiji, Vishnu Hosur
Published 2021-08-01

Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice.

by Madelyn R Schmidt, Michael C Appel, Lisa J Giassi, Dale L Greiner, Leonard D Shultz, Robert T Woodland
Published 2008-09-01

Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.

by Smita Jaiswal, Todd Pearson, Heather Friberg, Leonard D Shultz, Dale L Greiner, Alan L Rothman, Anuja Mathew
Published 2009-10-01

RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?

by Vishnu Hosur, Michelle L. Farley, Benjamin E. Low, Lisa M. Burzenski, Leonard D. Shultz, Michael V. Wiles
Published 2018-07-01

Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status

by Peishan Li, Ming Lu, Jiayuan Shi, Li Hua, Zheng Gong, Qing Li, Leonard D. Shultz, Guangwen Ren
Published 2020-09-01

Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation

by Vishnu Hosur, Benjamin E. Low, Daniel Li, Grace A. Stafford, Vivek Kohar, Leonard D. Shultz, Michael V. Wiles
Published 2020-07-01

P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer

by Hira Lal Goel, Bryan Pursell, Leonard D. Shultz, Dale L. Greiner, Rolf A. Brekken, Craig W. Vander Kooi, Arthur M. Mercurio
Published 2016-03-01

Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling.

by Christopher S Potter, Zhe Wang, Kathleen A Silva, Victoria E Kennedy, Timothy M Stearns, Lisa Burzenski, Leonard D Shultz, Harm Hogenesch, John P Sundberg
Published 2014-01-01

Appearance of Human Plasma Cells Following Differentiation of Human B Cells in NOD/SCID Mouse Spleen

by Susumu Ikehara, M. Eric Gershwin, Hiroshi Miyakawa, Leonard D. Shultz, Miyuki Ishibashi, Aftab A. Ansari, Xiao-Song He, Zhe-Xiong Lian, Kentaro Kikuchi
Published 2003-01-01

Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice.

by Fei Cheng, Laura Twardowski, Kurt Reifenberg, Kerstin Winter, Antje Canisius, Eva Pross, Jianglin Fan, Edgar Schmitt, Leonard D Shultz, Karl J Lackner, Michael Torzewski
Published 2016-01-01

Increased Frequency of Pre–Pro B Cells in the Bone Marrow of New Zealand Black (NZB) Mice: Implications for aDevelopmental Block in B Cell Differentiation

by Zhe-Xiong Lian, Hiroto Kita, Tomoyuki Okada, Tom Hsu, Leonard D. Shultz, Kenneth Dorshkind, Aftab A. Ansari, Susumu Ikehara, Mitsuru Naiki, M. Eric Gershwin
Published 2002-01-01

Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis.

by Richard B Bankert, Sathy V Balu-Iyer, Kunle Odunsi, Leonard D Shultz, Raymond J Kelleher, Jennifer L Barnas, Michelle Simpson-Abelson, Robert Parsons, Sandra J Yokota
Published 2011-01-01

A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation.

by Lihong Zhao, Stefka D Spassieva, Thomas J Jucius, Leonard D Shultz, H Elizabeth Shick, Wendy B Macklin, Yusuf A Hannun, Lina M Obeid, Susan L Ackerman
Published 2011-05-01

Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells

by Hira Lal Goel, Tatiana Gritsko, Bryan Pursell, Cheng Chang, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Leslie M. Shaw, Arthur M. Mercurio
Published 2014-05-01

A Comparative Analysis of the Murine Thymic Microenvironment in Normal, Autoimmune, andImmunodeficiency States

by Yuichi Takeoka, Shao-Yuan Chen, Richard L. Boyd, Koichi Tsuneyama, Nobuhisa Taguchi, Shinji Morita, Hisashi Yago, Seishi Suehiro, Aftab A. Ansari, Leonard D. Shultz, M. Eric Gershwin
Published 1997-01-01

Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.

by Gregory C Ippolito, Kam Hon Hoi, Sai T Reddy, Sean M Carroll, Xin Ge, Tobias Rogosch, Michael Zemlin, Leonard D Shultz, Andrew D Ellington, Carla L Vandenberg, George Georgiou
Published 2012-01-01

Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice

by Erica B Schleifman, Nicole Ali McNeer, Andrew Jackson, Jennifer Yamtich, Michael A Brehm, Leonard D Shultz, Dale L Greiner, Priti Kumar, W Mark Saltzman, Peter M Glazer
Published 2013-01-01