Tackling HLA Deficiencies Head on with Oncolytic Viruses

by Kerry Fisher, Ahmet Hazini, Leonard W. Seymour
Published 2021-02-01

Convergent Evolution by Cancer and Viruses in Evading the NKG2D Immune Response

by Richard Baugh, Hena Khalique, Leonard W. Seymour
Published 2020-12-01

MicroRNA controlled adenovirus mediates anti-cancer efficacy without affecting endogenous microRNA activity.

by Ryan Cawood, Suet-Ling Wong, Ying Di, Dilair F Baban, Leonard W Seymour
Published 2011-01-01

A Rapid-Response Humoral Vaccine Platform Exploiting Pre-Existing Non-Cognate Populations of Anti-Vaccine or Anti-Viral CD4+ T Helper Cells to Confirm B Cell Activation.

by Thomas Hills, Phillip G Jakeman, Robert C Carlisle, Paul Klenerman, Leonard W Seymour, Ryan Cawood
Published 2016-01-01

Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells.

by Ryan Cawood, Hannah H Chen, Fionnadh Carroll, Miriam Bazan-Peregrino, Nico van Rooijen, Leonard W Seymour
Published 2009-05-01

Combining Oncolytic Adenovirus with Radiation—A Paradigm for the Future of Radiosensitization

by Sean M. O’Cathail, Tzveta D. Pokrovska, Timothy S. Maughan, Kerry D. Fisher, Leonard W. Seymour, Maria A. Hawkins
Published 2017-07-01

Oncolytic herpesvirus expressing PD-L1 BiTE for cancer therapy: exploiting tumor immune suppression as an opportunity for targeted immunotherapy

by Hena Khalique, Richard Baugh, Arthur Dyer, Eleanor M. Scott, Sally Frost, Sarah Larkin, Janet Lei-Rossmann, Leonard W. Seymour
Published 2021-04-01

Nanomedicines for the Delivery of Biologics

by John Wahlich, Arpan Desai, Francesca Greco, Kathryn Hill, Arwyn T. Jones, Randall J. Mrsny, Gianfranco Pasut, Yvonne Perrie, F. Philipp Seib, Leonard W. Seymour, Ijeoma F. Uchegbu
Published 2019-05-01

Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators

by Arthur Dyer, Ying Di, Hugo Calderon, Sam Illingworth, Gray Kueberuwa, Alison Tedcastle, Phil Jakeman, Suet Lin Chia, Alice Brown, Michael A. Silva, David Barlow, John Beadle, Terry Hermiston, David J.P. Ferguson, Brian Champion, Kerry D. Fisher, Leonard W. Seymour
Published 2017-03-01