The utility of in vitro trials that use Caco-2 cell systems as a replacement for animal intestinal permeability and human bioequivalence measurements in drug development

by Margarida Estudante, Cristina de Mello-Sampayo, Selma Sahin, José Morais, Leslie Z. Benet
Published 2015-04-01

TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling

by Alan R. Wolfe, R. Jeffrey Neitz, Mark Burlingame, Brian M. Suzuki, KC Lim, Mark Scheideler, David L. Nelson, Leslie Z. Benet, Conor R. Caffrey
Published 2018-12-01

Ascorbic acid metabolites are involved in intraocular pressure control in the general population

by Pirro G. Hysi, Anthony P. Khawaja, Cristina Menni, Bani Tamraz, Nick Wareham, Kay-Tee Khaw, Paul J. Foster, Leslie Z. Benet, Tim D. Spector, Chris J. Hammond
Published 2019-01-01

Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence

by Monica Gandhi, Peter Bacchetti, Warren C. Rodrigues, Matthew Spinelli, Catherine A. Koss, Paul K. Drain, Jared M. Baeten, Nelly R. Mugo, Kenneth Ngure, Leslie Z. Benet, Hideaki Okochi, Guohong Wang, Michael Vincent
Published 2018-08-01