Pharmacological Activity and Clinical Use of PDRN

by Francesco Squadrito, Alessandra Bitto, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Letteria Minutoli, Domenica Altavilla
Published 2017-04-01

Health Potential of <i>Aloe vera</i> against Oxidative Stress Induced Corneal Damage: An “In Vitro<i>”</i> Study

by Ida Ceravolo, Federica Mannino, Natasha Irrera, Francesco Squadrito, Domenica Altavilla, Giorgia Ceravolo, Giovanni Pallio, Letteria Minutoli
Published 2021-02-01

The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury

by Natasha Irrera, Massimo Russo, Giovanni Pallio, Alessandra Bitto, Federica Mannino, Letteria Minutoli, Domenica Altavilla, Francesco Squadrito
Published 2020-08-01

Combined Treatment with Polynucleotides and Hyaluronic Acid Improves Tissue Repair in Experimental Colitis

by Giovanni Pallio, Alessandra Bitto, Antonio Ieni, Natasha Irrera, Federica Mannino, Socrate Pallio, Domenica Altavilla, Francesco Squadrito, Carmelo Scarpignato, Letteria Minutoli
Published 2020-10-01

Levels of Heavy Metals in Adolescents Living in the Industrialised Area of Milazzo-Valle del Mela (Northern Sicily)

by Monica Interdonato, Alessandra Bitto, Gabriele Pizzino, Natasha Irrera, Giovanni Pallio, Anna Mecchio, Antonino Cuspilici, Letteria Minutoli, Domenica Altavilla, Francesco Squadrito
Published 2014-01-01

CO2 Pneumoperitoneum Preserves β-Arrestin 2 Content and Reduces High Mobility Group Box-1 (HMGB-1) Expression in an Animal Model of Peritonitis

by Angela Simona Montalto, Alessandra Bitto, Letteria Minutoli, Pietro Impellizzeri, Gaetano Costa, Natasha Irrera, Gabriele Pizzino, Francesco Squadrito, Domenica Altavilla, Carmelo Romeo
Published 2015-01-01

Effects of Serenoa Repens, Selenium and Lycopene (Profluss&#174;) on chronic inflammation associated with Benign Prostatic Hyperplasia: results of &#8220;FLOG&#8221; (Flogosis and...

by Giuseppe Morgia, Sebastiano Cimino, Vincenzo Favilla, Giorgio Ivan Russo, Francesco Squadrito, Giuseppe Mucciardi, Lorenzo Masieri, Letteria Minutoli, Giuseppe Grosso, Tommaso Castelli
Published 2013-04-01

Antiosteoporotic Activity of Genistein Aglycone in Postmenopausal Women: Evidence from a Post-Hoc Analysis of a Multicenter Randomized Controlled Trial

by Vincenzo Arcoraci, Marco Atteritano, Francesco Squadrito, Rosario D’Anna, Herbert Marini, Domenico Santoro, Letteria Minutoli, Sonia Messina, Domenica Altavilla, Alessandra Bitto
Published 2017-02-01

The Association of Myo-Inositol and Selenium Contrasts Cadmium-Induced Thyroid C Cell Hyperplasia and Hypertrophy in Mice

by Salvatore Benvenga, Antonio Micali, Antonio Ieni, Alessandro Antonelli, Poupak Fallahi, Giovanni Pallio, Natasha Irrera, Francesco Squadrito, Giacomo Picciolo, Domenico Puzzolo, Letteria Minutoli
Published 2021-02-01

PDRN, a natural bioactive compound, blunts inflammation and positively reprograms healing genes in an “in vitro” model of oral mucositis

by Giacomo Picciolo, Federica Mannino, Natasha Irrera, Domenica Altavilla, Letteria Minutoli, Mario Vaccaro, Vincenzo Arcoraci, Violetta Squadrito, Giuseppe Picciolo, Francesco Squadrito, Giovanni Pallio
Published 2021-06-01

Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Steps of the Inflammatory Cascade in Polymicrobial Sepsis

by Gabriele Pizzino, Alessandra Bitto, Giovanni Pallio, Natasha Irrera, Federica Galfo, Monica Interdonato, Anna Mecchio, Filippo De Luca, Letteria Minutoli, Francesco Squadrito, Domenica Altavilla
Published 2015-01-01

Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland

by Elvira Ventura Spagnolo, Cristina Mondello, Luigi Cardia, Letteria Minutoli, Domenico Puzzolo, Alessio Asmundo, Vincenzo Macaione, Angela Alibrandi, Consuelo Malta, Gennaro Baldino, Antonio Micali
Published 2019-06-01

A Flavonoid-Rich Extract from Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, Shows Protective Effects in a Murine Model of Cadmium-Induced Testicular Injury

by Nadia Ferlazzo, Antonio Micali, Herbert Ryan Marini, Josè Freni, Giuseppe Santoro, Domenico Puzzolo, Francesco Squadrito, Giovanni Pallio, Michele Navarra, Santa Cirmi, Letteria Minutoli
Published 2021-04-01

MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells

by Giovanni Pallio, Angela D’Ascola, Luigi Cardia, Federica Mannino, Alessandra Bitto, Letteria Minutoli, Giacomo Picciolo, Violetta Squadrito, Natasha Irrera, Francesco Squadrito, Domenica Altavilla
Published 2021-08-01

Targeting Adenosine Receptor by Polydeoxyribonucleotide: An Effective Therapeutic Strategy to Induce White-to-Brown Adipose Differentiation and to Curb Obesity

by Federica Mannino, Giovanni Pallio, Alessandra Bitto, Domenica Altavilla, Letteria Minutoli, Violetta Squadrito, Vincenzo Arcoraci, Domenico Antonio Giorgi, Igor Pirrotta, Francesco Squadrito, Natasha Irrera
Published 2021-07-01

PDRN, a Bioactive Natural Compound, Ameliorates Imiquimod-Induced Psoriasis through NF-κB Pathway Inhibition and Wnt/β-Catenin Signaling Modulation

by Natasha Irrera, Alessandra Bitto, Mario Vaccaro, Federica Mannino, Violetta Squadrito, Giovanni Pallio, Vincenzo Arcoraci, Letteria Minutoli, Antonio Ieni, Maria Lentini, Domenica Altavilla, Francesco Squadrito
Published 2020-02-01

Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes

by Giuseppina T. Russo, Letteria Minutoli, Alessandra Bitto, Domenica Altavilla, Eugenio Alessi, Annalisa Giandalia, Elisabetta L. Romeo, Maria Francesca Stagno, Francesco Squadrito, Domenico Cucinotta, Jacob Selhub
Published 2012-01-01

Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy)

by Gabriele Pizzino, Alessandra Bitto, Monica Interdonato, Federica Galfo, Natasha Irrera, Anna Mecchio, Giovanni Pallio, Vincenzo Ramistella, Filippo De Luca, Letteria Minutoli, Francesco Squadrito, Domenica Altavilla
Published 2014-01-01

ROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic Strategies

by Mariagrazia Rinaldi, Maria Caffo, Letteria Minutoli, Herbert Marini, Rosaria Viola Abbritti, Francesco Squadrito, Vincenzo Trichilo, Andrea Valenti, Valeria Barresi, Domenica Altavilla, Marcello Passalacqua, Gerardo Caruso
Published 2016-06-01

Caspase 9 and Caspase 3 Immunohistochemical Pattern in Skeletal and Cardiac Muscles at Different Times after Death: An Experimental Study on PMI Estimation

by Cristina Mondello, Chiara Stassi, Letteria Minutoli, Gennaro Baldino, Angela Alibrandi, Giovanni Francesco Spatola, Maria Laura Uzzo, Antonio Micali, Domenico Puzzolo, Alessio Asmundo, Elvira Ventura Spagnolo
Published 2021-06-01