Asymmetrically regulated transcription profiles (ART) Biological significance Gene Expression Profiling Genes Genes, Essential Housekeeping gene Least trimmed squares regression Linear modeling Mode Multi reference Multi-reference Multiple references Normalization RNA RNA sequencing RNA-Seq RNA-seq Representative sample Sequence Analysis, RNA Skewness Statistical regression Whole Exome Sequencing article cell cycle essential gene gene expression profiling genetic transcription housekeeping gene licence sequence analysis