Hyperglycemia-Induced Dysregulated Fusion Intermediates in Insulin-Secreting Cells Visualized by Super-Resolution Microscopy

by Guoyi Yang, Liuju Li, Yanmei Liu, Yanmei Liu, Kuo Liang, Lisi Wei, Liangyi Chen, Liangyi Chen, Liangyi Chen, Liangyi Chen
Published 2021-04-01

pHmScarlet is a pH-sensitive red fluorescent protein to monitor exocytosis docking and fusion steps

by Anyuan Liu, Xiaoshuai Huang, Wenting He, Fudong Xue, Yanrui Yang, Jiajia Liu, Liangyi Chen, Lin Yuan, Pingyong Xu
Published 2021-03-01

Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose

by Yulin Zhang, Chengsheng Han, Wenzhen Zhu, Guoyi Yang, Xiaohong Peng, Sohum Mehta, Jin Zhang, Liangyi Chen, Yanmei Liu
Published 2021-09-01

Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells.

by Li Xie, Subhankar Dolai, Youhou Kang, Tao Liang, Huanli Xie, Tairan Qin, Lu Yang, Liangyi Chen, Herbert Y Gaisano
Published 2016-01-01

Endoplasmic Reticulum Stress Activation in Alport Syndrome Varies Between Genotype and Cell Type

by Cong Wang, Shenghui Liang, Shijia Xing, Ke Xu, Huijie Xiao, Haiyue Deng, Xiaoyuan Wang, Liangyi Chen, Jie Ding, Fang Wang
Published 2020-02-01

Spectrin-based membrane skeleton supports ciliogenesis.

by Ru Jia, Dongdong Li, Ming Li, Yongping Chai, Yufan Liu, Zhongyun Xie, Wenxin Shao, Chao Xie, Liuju Li, Xiaoshuai Huang, Liangyi Chen, Wei Li, Guangshuo Ou
Published 2019-07-01

Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules

by Xiaofan Han, Pin Li, Zhenghao Yang, Xiaoshuai Huang, Guoqin Wei, Yujie Sun, Xuya Kang, Xueting Hu, Qiuping Deng, Liangyi Chen, Aibin He, Yingqing Huo, Dong Li, Eric Betzig, Jincai Luo
Published 2017-03-01

In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development

by Jia Zhao, Weijian Zong, Yiwen Zhao, Dongzhou Gou, Shenghui Liang, Jiayu Shen, Yi Wu, Xuan Zheng, Runlong Wu, Xu Wang, Fuzeng Niu, Aimin Wang, Yunfeng Zhang, Jing-Wei Xiong, Liangyi Chen, Yanmei Liu
Published 2019-01-01

A unified deep-learning network to accurately segment insulin granules of different animal models imaged under different electron microscopy methodologies

by Xiaoya Zhang, Xiaohong Peng, Chengsheng Han, Wenzhen Zhu, Lisi Wei, Yulin Zhang, Yi Wang, Xiuqin Zhang, Hao Tang, Jianshe Zhang, Xiaojun Xu, Fengping Feng, Yanhong Xue, Erlin Yao, Guangming Tan, Tao Xu, Liangyi Chen
Published 2018-10-01

A subcellular map of the human kinome

by Haitao Zhang, Xiaolei Cao, Mei Tang, Guoxuan Zhong, Yuan Si, Haidong Li, Feifeng Zhu, Qinghua Liao, Liuju Li, Jianhui Zhao, Jia Feng, Shuaifeng Li, Chenliang Wang, Manuel Kaulich, Fangwei Wang, Liangyi Chen, Li Li, Zongping Xia, Tingbo Liang, Huasong Lu, Xin-Hua Feng, Bin Zhao
Published 2021-05-01

Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders

by Yao Xiao, Can Wang, Jia-Yu Chen, Fujian Lu, Jue Wang, Ning Hou, Xiaomin Hu, Fanxin Zeng, Dongwei Ma, Xueting Sun, Yi Ding, Yan Zhang, Wen Zheng, Yuli Liu, Haibao Shang, Wenzhen Zhu, Chensheng Han, Yulin Zhang, Kunfu Ouyang, Liangyi Chen, Ju Chen, Rui-Ping Xiao, Chuan-Yun Li, Xiuqin Zhang
Published 2018-05-01