The Protein Trinity: Structure/Function Relationships That Include Intrinsic Disorder

by A. Keith Dunker, Celeste J. Brown, Celeste J. David Lawson, Lilia M. Iakoucheva-Sebat, Slobodan Vucetic, Zoran Obradovic
Published 2002-01-01

Disease-associated mutations disrupt functionally important regions of intrinsic protein disorder.

by Vladimir Vacic, Phineus R L Markwick, Christopher J Oldfield, Xiaoyue Zhao, Chad Haynes, Vladimir N Uversky, Lilia M Iakoucheva
Published 2012-01-01

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes.

by Chad Haynes, Christopher J Oldfield, Fei Ji, Niels Klitgord, Michael E Cusick, Predrag Radivojac, Vladimir N Uversky, Marc Vidal, Lilia M Iakoucheva
Published 2006-08-01

Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome.

by Kymberleigh A Pagel, Danny Antaki, AoJie Lian, Matthew Mort, David N Cooper, Jonathan Sebat, Lilia M Iakoucheva, Sean D Mooney, Predrag Radivojac
Published 2019-06-01

Inferring the molecular and phenotypic impact of amino acid variants with MutPred2

by Vikas Pejaver, Jorge Urresti, Jose Lugo-Martinez, Kymberleigh A. Pagel, Guan Ning Lin, Hyun-Jun Nam, Matthew Mort, David N. Cooper, Jonathan Sebat, Lilia M. Iakoucheva, Sean D. Mooney, Predrag Radivojac
Published 2020-11-01

Oligogenic Effects of 16p11.2 Copy-Number Variation on Craniofacial Development

by Yuqi Qiu, Thomas Arbogast, Sandra Martin Lorenzo, Hongying Li, Shih C. Tang, Ellen Richardson, Oanh Hong, Shawn Cho, Omar Shanta, Timothy Pang, Christina Corsello, Curtis K. Deutsch, Claire Chevalier, Erica E. Davis, Lilia M. Iakoucheva, Yann Herault, Nicholas Katsanis, Karen Messer, Jonathan Sebat
Published 2019-09-01