Anti-cancer Therapies Employing IL-2 Cytokine Tumor Targeting: Contribution of Innate, Adaptive and Immunosuppressive Cells in the Anti-tumor Efficacy

by Lorenzo Mortara, Enrica Balza, Antonino Bruno, Alessandro Poggi, Paola Orecchia, Barbara Carnemolla
Published 2018-12-01

Natural Killer Cells as Key Players of Tumor Progression and Angiogenesis: Old and Novel Tools to Divert Their Pro-Tumor Activities into Potent Anti-Tumor Effects

by Barbara Bassani, Denisa Baci, Matteo Gallazzi, Alessandro Poggi, Antonino Bruno, Lorenzo Mortara
Published 2019-04-01

Innate Immunity Effector Cells as Inflammatory Drivers of Cardiac Fibrosis

by Denisa Baci, Annalisa Bosi, Luca Parisi, Giuseppe Buono, Lorenzo Mortara, Giuseppe Ambrosio, Antonino Bruno
Published 2020-09-01

Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy

by Adriana Albini, Adriana Albini, Antonino Bruno, Douglas M. Noonan, Douglas M. Noonan, Lorenzo Mortara
Published 2018-04-01

Immunological Drivers in Graves' Disease: NK Cells as a Master Switcher

by Daniela Gallo, Eliana Piantanida, Matteo Gallazzi, Luigi Bartalena, Maria Laura Tanda, Antonino Bruno, Lorenzo Mortara
Published 2020-07-01

Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and Pro-angiogenic Activities: Roles in Tumor Progression

by Antonino Bruno, Lorenzo Mortara, Denisa Baci, Douglas M. Noonan, Douglas M. Noonan, Adriana Albini, Adriana Albini
Published 2019-04-01

Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response.

by Barbara Morandi, Lorenzo Mortara, Laura Chiossone, Roberto S Accolla, Maria Cristina Mingari, Lorenzo Moretta, Alessandro Moretta, Guido Ferlazzo
Published 2012-01-01

The Ovarian Cancer Tumor Immune Microenvironment (TIME) as Target for Therapy: A Focus on Innate Immunity Cells as Therapeutic Effectors

by Denisa Baci, Annalisa Bosi, Matteo Gallazzi, Manuela Rizzi, Douglas M. Noonan, Alessandro Poggi, Antonino Bruno, Lorenzo Mortara
Published 2020-04-01

Macrophage Polarization in Chronic Inflammatory Diseases: Killers or Builders?

by Luca Parisi, Elisabetta Gini, Denisa Baci, Marco Tremolati, Matteo Fanuli, Barbara Bassani, Giampietro Farronato, Antonino Bruno, Lorenzo Mortara
Published 2018-01-01

Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategi...

by Denisa Baci, Antonino Bruno, Caterina Cascini, Matteo Gallazzi, Lorenzo Mortara, Fausto Sessa, Giuseppe Pelosi, Adriana Albini, Douglas M. Noonan
Published 2019-11-01

Overexpression of Murine <i>Rnaset2</i> in a Colon Syngeneic Mouse Carcinoma Model Leads to Rebalance of Intra-Tumor M1/M2 Macrophage Ratio, Activation of T Cells, Delayed Tumor Gr...

by Annarosaria De Vito, Paola Orecchia, Enrica Balza, Daniele Reverberi, Debora Scaldaferri, Roberto Taramelli, Douglas M. Noonan, Francesco Acquati, Lorenzo Mortara
Published 2020-03-01

BRAF Mutations in an Italian Regional Population: Implications for the Therapy of Thyroid Cancer

by Eleonora Monti, Michela Bovero, Lorenzo Mortara, Giorgia Pera, Simonetta Zupo, Elena Gugiatti, Mariella Dono, Barbara Massa, Gian Luca Ansaldo, Giusti Massimo
Published 2015-01-01

Innate Immune Response Regulation by the Human RNASET2 Tumor Suppressor Gene

by Francesco Acquati, Lorenzo Mortara, Annarosaria De Vito, Denisa Baci, Adriana Albini, Adriana Albini, Marco Cippitelli, Roberto Taramelli, Douglas M. Noonan, Douglas M. Noonan
Published 2019-11-01

Prostate Cancer Peripheral Blood NK Cells Show Enhanced CD9, CD49a, CXCR4, CXCL8, MMP-9 Production and Secrete Monocyte-Recruiting and Polarizing Factors

by Matteo Gallazzi, Denisa Baci, Lorenzo Mortara, Annalisa Bosi, Giuseppe Buono, Angelo Naselli, Andrea Guarneri, Federico Dehò, Paolo Capogrosso, Adriana Albini, Douglas M. Noonan, Douglas M. Noonan, Antonino Bruno
Published 2021-01-01

The Proangiogenic Phenotype of Natural Killer Cells in Patients with Non-Small Cell Lung Cancer

by Antonino Bruno, Chiara Focaccetti, Arianna Pagani, Andrea S. Imperatori, Marco Spagnoletti, Nicola Rotolo, Anna Rita Cantelmo, Francesca Franzi, Carlo Capella, Guido Ferlazzo, Lorenzo Mortara, Adriana Albini, Douglas M. Noonan
Published 2013-02-01

Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization

by Annalisa Bosi, Silvia Zanellato, Barbara Bassani, Adriana Albini, Alessandra Musco, Maria Cattoni, Matteo Desio, Elisa Nardecchia, Davide Giuseppe D’Urso, Andrea Imperatori, Lorenzo Dominioni, Douglas M. Noonan, Lorenzo Mortara, Antonino Bruno
Published 2018-01-01