Voltage-Gated Sodium Channel β1/β1B Subunits Regulate Cardiac Physiology and Pathophysiology

by Nnamdi Edokobi, Lori L. Isom
Published 2018-04-01

Na+ channel β subunits: Overachievers of the ion channel family

by William J Brackenbury, Lori L Isom
Published 2011-09-01

Ordered Assembly of the Adhesive and Electrochemical Connections within Newly Formed Intercalated Disks in Primary Cultures of Adult Rat Cardiomyocytes

by Sarah B. Geisler, Kathleen J. Green, Lori L. Isom, Sasha Meshinchi, Jeffrey R. Martens, Mario Delmar, Mark W. Russell
Published 2010-01-01

Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.

by David S Auerbach, Julie Jones, Brittany C Clawson, James Offord, Guy M Lenk, Ikuo Ogiwara, Kazuhiro Yamakawa, Miriam H Meisler, Jack M Parent, Lori L Isom
Published 2013-01-01

Excitatory and inhibitory neuron defects in a mouse model of Scn1b‐linked EIEE52

by Jacob M. Hull, Heather A. O’Malley, Chunling Chen, Yukun Yuan, Nicholas Denomme, Alexandra A. Bouza, Charles Anumonwo, Luis F. Lopez‐Santiago, Lori L. Isom
Published 2020-11-01

Scn1b deletion in adult mice results in seizures and SUDEP

by Heather A. O'Malley, Jacob M. Hull, Brittany C. Clawson, Chunling Chen, Gic Owens‐Fiestan, Margaret B. Jameson, Sara J. Aton, Jack M. Parent, Lori L. Isom
Published 2019-06-01

Sodium channel β1 subunits participate in regulated intramembrane proteolysis-excitation coupling

by Alexandra A. Bouza, Nnamdi Edokobi, Samantha L. Hodges, Alexa M. Pinsky, James Offord, Lin Piao, Yan-Ting Zhao, Anatoli N. Lopatin, Luis F. Lopez-Santiago, Lori L. Isom
Published 2021-02-01

SCN1B‐linked early infantile developmental and epileptic encephalopathy

by Alec Aeby, Claudine Sculier, Alexandra A. Bouza, Brandon Askar, Damien Lederer, Anne‐Sofie Schoonjans, Marc Vander Ghinst, Berten Ceulemans, James Offord, Luis F. Lopez‐Santiago, Lori L. Isom
Published 2019-12-01

Channelopathy as a SUDEP Biomarker in Dravet Syndrome Patient-Derived Cardiac Myocytes

by Chad R. Frasier, Helen Zhang, James Offord, Louis T. Dang, David S. Auerbach, Huilin Shi, Chunling Chen, Alica M. Goldman, L. Lee Eckhardt, Vassilios J. Bezzerides, Jack M. Parent, Lori L. Isom
Published 2018-09-01

The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation

by Rengasayee Veeraraghavan, Gregory S Hoeker, Anita Alvarez-Laviada, Daniel Hoagland, Xiaoping Wan, D Ryan King, Jose Sanchez-Alonso, Chunling Chen, Jane Jourdan, Lori L Isom, Isabelle Deschenes, James W Smyth, Julia Gorelik, Steven Poelzing, Robert G Gourdie
Published 2018-08-01

Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome

by Sam A. Booker, Laura Simões de Oliveira, Natasha J. Anstey, Zrinko Kozic, Owen R. Dando, Adam D. Jackson, Paul S. Baxter, Lori L. Isom, Diane L. Sherman, Giles E. Hardingham, Peter J. Brophy, David J.A. Wyllie, Peter C. Kind
Published 2020-08-01